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Citation: ZHANG Ai-Ping, SUN Yan-Ping, FAN Cai-Mei. Photocatalytic Killing Effect of Nanometer Titanium Dioxide on Human Gastric Cancer Cell[J]. Chinese Journal of Applied Chemistry, ;2004, 21(11): 1109-1112. shu

Photocatalytic Killing Effect of Nanometer Titanium Dioxide on Human Gastric Cancer Cell

1.
Department of Chemical Engineering, Taiyuan University of Technology, Taiyuan 030024

Corresponding author: SUN Yan-Ping,
Received Date: 30 December 2003
Available Online: 21 March 2004
Fund Project: 国家自然科学基金资助项目(29776032) (29776032)

Nanometer titanium dioxide was prepared by coating technique and characterized by XRD and SEM(anatase, average size 22.7 nanometer). The experiment of the photocatalytic killing human gastric cancer cell line was conducted in vitro with titanium dioxide as a photocatalyst. The viability of the cancer cells was detected by a flow cytometer(FCM) and fluorescence staining method. The results showed that human gastric cancer cell line BGC-823 were remarkbly killed by the photocatalytic oxidetion reaction under irradiation of 300~400nm UV light. 80% of the cells were killed when the irradiation intensity was 1.06×10^-3 W/cm², with 9.8×10^-7 g/cm² TiO₂ coated as a photocatalyst, and 40 min irradiation time.
- nanometer TiO₂,
- photocatalytic oxidization,
- human gastric cancer cell(BGC-823),
- anticancer
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