Citation:
WANG Rui-Xin, GUO Jian-Feng, GAO Bao-Jiao. Antibacterial Property and Mechanism of Macromolecular Quaternary Pyridine Salt[J]. Chinese Journal of Applied Chemistry,
;2006, 23(2): 184-187.
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This paper reports the antibacterial property of quaternary copolymer of 4-vinyl pyridine and acrylamide (Quaternary P(4VP-co-AM),QCVA) against Escherichia Coli,the influence of pH value on the antibacterial property of QCVA with the method of plate counting live bacterium,and the antibacterial mechanism of QCVA by measuring the activities of β-D-galactosidase and TTC-DHE.The experimental results indicate that cationic polyacrylamide of quaternary pyridine salt-type possesses excellent antibacterial property.In addition in a certain pH range,the greater the pH value,the better the antibacterial effect of QCVA.The measured results of the activities of β-D-galactosidase and TTC-DHE show that the antibacterial effect of QCVA is mainly based on sterilization action besides restraining action.
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