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Citation: ZHANG Xiu-Li, LÜ Xian-Hai, LIU Tie-Bing, JIANG Wan-Quan, TAN Hua-Rong. Syntheses and Antifungal Activities of α-Napthaleneacetic Acid Derivatives[J]. Chinese Journal of Applied Chemistry, ;2006, 23(12): 1364-1367. shu

Syntheses and Antifungal Activities of α-Napthaleneacetic Acid Derivatives

1.
a College of Science, Anhui Agricultural University, Hefei 230036;
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b Shanghai Applied Radiation Institute, Shanghai University, Shanghai;
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c Department of Chemistry, University of Science and Technology of China, Hefei

Corresponding author: ZHANG Xiu-Li,
Received Date: 22 December 2005
Available Online: 30 March 2006
Fund Project: 安徽省教育厅科研项目(2005KJ122) (2005KJ122)合肥市重点科技项目(合科2006[27])资助 (合科2006[27])

With α-napthaleneacetic acid as precursor,three thiourea derivatives and three carboxamides derivatives were synthesized by solid-liquid phase transfer catalytic reaction.Compounds 3a,3b,3d,3e,3f are new compounds.The structures were confirmed by means of IR,¹H NMR,MS and elemental analysis.The results of biological test show that all of these compounds have good antifungicidal activities.The anti-fungal activities to Fusarium moniliforme could reach 70% when their centrations is around 50 mg/L.
- α-napthaleneacetic acid,
- acyl thiourea,
- carboxamides,
- phase transfer catalysis,
- synthesis,
- antifungal activity
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