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Citation: ZHOU Xiao-Hu, LUO Hui, ZHOU Zhen. Synthesis of Chitosan-Gelatin Copolymer in the Presence of MTGase and Its Bacteriostasis Properities[J]. Chinese Journal of Applied Chemistry, ;2008, 25(3): 334-339. shu

Synthesis of Chitosan-Gelatin Copolymer in the Presence of MTGase and Its Bacteriostasis Properities

1.
Department of Chemical Engineering, Chongqing University, Chongqing 400044

Corresponding author: ZHOU Xiao-Hu,
Received Date: 26 March 2007
Available Online: 18 August 2007
Fund Project:

Chitosan-Gelatin copolymer was synthesized with MTGase as catalyst from chitosan and gelatin.IR and DTA data indicated that chitosan and gelatin were linked via schiff bonds to yield the copolymer,the branched structure of which was confimed by AFM.The isoelectric point of the copolymer was 8.43,the average molelular mass was 36~38 KDa,and the solubility was 8.7 g/L in water at pH=5.0.The yield increased with the ratio of gelatin to chitosan,and bacteriostasis of the copolymer to Staphylococcus aureus decreased.When the ratio was 0.6,pH value was 6.0,temperature was 50℃,and reaction time was 40 min,the yield of the copolymer was 64.5%.Bacteriostasis to Staphylococcus aureus for 1% copolymer resolution was 70% that of chitosan.
- chitosan,
- gelatin,
- polymer,
- MTGase,
- bacteriostasis
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