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Citation: CUI Ping, LIU Xin-Hua, ZHI Li-Ping, WANG Xiao-Hu, SONG Bao-An, ZUO Ren-Bing. Synthesis and Biological Activity of Novel 5-Aryl-N-pyrazole Oxime Ester Derivatives[J]. Chinese Journal of Applied Chemistry, ;2008, 25(7): 820-824. shu

Synthesis and Biological Activity of Novel 5-Aryl-N-pyrazole Oxime Ester Derivatives

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a Key laboratory of Anhui Educational Department, School of Chemistry and Chemical Engineering, Anhui University of Technology, Maanshan 243002;
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b Faculty of Mathematics & Physics, Anhui University of Technology, Maanshan;
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c MOE Key Laboratory of Green Pesticides and Agriculture Bioengineering, Guizhou University, Guiyang 550025

Corresponding author: SONG Bao-An,
Received Date: 20 July 2007
Available Online: 17 November 2007
Fund Project: 安徽省自然科学基金资助项目(070416274X) (070416274X)安徽省高等学校自然科学研究项目(2006KJ104B) (2006KJ104B)安徽工业大学SRTP项目(07016) (07016)

4-(2-Hydroxyphenyl) but-3-en-2-one was prepared from 2-hydroxybenzaldehyde,which then reacted with hydrazine monohydrate.Ten new 1-(5-(2-hydroxy) phenyl)-3-methy-4,5-dihydropyrazol-1-yl) ethanone oxime ester derivatives were synthesized and characterized by elemental analysis,IR and ¹H NMR.The compounds were evaluated for their fungicidal activity.The results showed that the title compounds displayed good fungicidal activity against Gibberella (inhibition ratio of compounds 5f towards Gibberella at 50 mg/L was 81.3%);compounds 5g and 5i showed certain fungicidal activity against H.Oryzae.The title compounds showed poor fungicidal activity against P.oryza.
- pyrazole oxime ester,
- synthesis,
- fungicidal activity
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