Home

Citation: WANG Jun, ZHANG Yuan-Yuan, ZHANG Lei, WANG Xiao-Fang, XU Rui, GUO Ying, ZHANG Xiang-Dong. Sonodynamic Damage of Bovine Serum Albumin(BSA) under Ultrasonic Irradiation in the Presence of Methylene Blue(MB)[J]. Chinese Journal of Applied Chemistry, ;2008, 25(12): 1399-1403. shu

Sonodynamic Damage of Bovine Serum Albumin(BSA) under Ultrasonic Irradiation in the Presence of Methylene Blue(MB)

1.
a Chemistry;
2.
b Department;Pharmaceutics Department, Liaoning University, Shenyang 110036

Corresponding author: WANG Jun,
Received Date: 26 November 2007
Available Online: 9 March 2008
Fund Project: 国家自然科学基金(20371023) (20371023)辽宁省教育厅自然科学基金(2004C018)资助项目 (2004C018)

The damage of bovine serum albumin(BSA) molecules under the action of methylene blue(MB) activated by ultrasonic irradiation was detected by UV-Vis spectroscopy and fluorescence spectroscopy,and influencing factors such as ultrasonic irradiation time,MB concentration and pH value on the damage of BSA molecules were also investigated.The results show that under certain conditions,the damage of BSA molecules was enhanced with the increases of the ultrasonic irradiation time,MB concentration,and pH value,that is,UV-Vis spectra showed more and more obvious hyperchromic effect and fluorescence spectra exhibited more and more obvious quenching effect.In addition,the possible mechanism of sonodynamic damage of BSA molecules from MB activated by ultrasound was also discussed in this work.The result has certain significance for the application of photosensitive drugs to sonodynamic therapy(SDT).
- ultrasound,
- methylene blue(MB),
- bovine serum albumin(BSA),
- damage
1. [1]
  Bing LIU , Huang ZHANG , Hongliang HAN , Changwen HU , Yinglei ZHANG . Visible light degradation of methylene blue from water by triangle Au@TiO₂ mesoporous catalyst. Chinese Journal of Inorganic Chemistry, 2024, 40(5): 941-952. doi: 10.11862/CJIC.20230398
2. [2]
  Yichang Liu , Li An , Dan Qu , Zaicheng Sun . “双碳”背景下的综合设计实验——以PbCrO₄催化甲基蓝的光降解速率常数测定为例. University Chemistry, 2025, 40(6): 222-229. doi: 10.12461/PKU.DXHX202407105
3. [3]
  Peiyu Zhang , Aixin Song , Jingcheng Hao , Jiwei Cui . 高频超声法制备聚多巴胺薄膜综合实验. University Chemistry, 2025, 40(6): 210-214. doi: 10.12461/PKU.DXHX202407081
4. [4]
  Ruiying Zhao , Shuheng Luo , Jinke Li , Junjie Zhang , Min Zhu , Yang Li , Yanhong Bai , Yinhuan Li , Lijuan Wang . Ultrasonic-Assisted Synthesis of Rosacetal: A Comprehensive Research-Oriented Organic Chemistry Experiment. University Chemistry, 2025, 40(11): 300-309. doi: 10.12461/PKU.DXHX202412075
5. [5]
  Zhangshu Wang , Xin Zhang , Jixin Han , Xuebing Fang , Xiufeng Zhao , Zeyu Gu , Jinjun Deng . Exploration and Design of Experimental Teaching on Ultrasonic-Enhanced Synergistic Treatment of Ternary Composite Flooding Produced Water. University Chemistry, 2024, 39(5): 116-124. doi: 10.3866/PKU.DXHX202310056
6. [6]
  Jie WEI , Qing ZHOU , Dandan DING , Xiang JING , Fei LI . Photothermal toxicity of Prussian blue nanoparticles to cervical cancer cells. Chinese Journal of Inorganic Chemistry, 2025, 41(11): 2345-2357. doi: 10.11862/CJIC.20240435
7. [7]
  Chi Li , Jichao Wan , Qiyu Long , Hui Lv , Ying Xiong . N-Heterocyclic Carbene (NHC)-Catalyzed Amidation of Aldehydes with Nitroso Compounds. University Chemistry, 2024, 39(5): 388-395. doi: 10.3866/PKU.DXHX202312016
8. [8]
  Xinhao Yan , Guoliang Hu , Ruixi Chen , Hongyu Liu , Qizhi Yao , Jiao Li , Lingling Li . Polyethylene Glycol-Ammonium Sulfate-Nitroso R Salt System for the Separation of Cobalt (II). University Chemistry, 2024, 39(6): 287-294. doi: 10.3866/PKU.DXHX202310073
9. [9]
  Zhuoya WANG , Le HE , Zhiquan LIN , Yingxi WANG , Ling LI . Multifunctional nanozyme Prussian blue modified copper peroxide: Synthesis and photothermal enhanced catalytic therapy of self-provided hydrogen peroxide. Chinese Journal of Inorganic Chemistry, 2024, 40(12): 2445-2454. doi: 10.11862/CJIC.20240194
10. [10]
  Fen Wang , Qi Yang , Qianfei Ye , Jichao Xiao . Synthesis of Sulfinamidines via the Oxidative Sulfonamination of Sulfenamides: A Recommended Comprehensive Organic Chemistry Experiment. University Chemistry, 2025, 40(11): 354-361. doi: 10.12461/PKU.DXHX202506059
11. [11]
  Tiantian MA , Sumei LI , Chengyu ZHANG , Lu XU , Yiyan BAI , Yunlong FU , Wenjuan JI , Haiying YANG . Methyl-functionalized Cd-based metal-organic framework for highly sensitive electrochemical sensing of dopamine. Chinese Journal of Inorganic Chemistry, 2024, 40(4): 725-735. doi: 10.11862/CJIC.20230351
12. [12]
  Xiaoning TANG , Junnan LIU , Xingfu YANG , Jie LEI , Qiuyang LUO , Shu XIA , An XUE . Effect of sodium alginate-sodium carboxymethylcellulose gel layer on the stability of Zn anodes. Chinese Journal of Inorganic Chemistry, 2024, 40(8): 1452-1460. doi: 10.11862/CJIC.20240191
13. [13]
  Mengyang LI , Hao XU , Zhonghao NIU , Chunhua GONG , Weihui ZHONG , Jingli XIE . Highly effective catalytic synthesis of β-amino alcohols by using viologen-polyoxometalate hybrid materials. Chinese Journal of Inorganic Chemistry, 2025, 41(7): 1294-1300. doi: 10.11862/CJIC.20250080
14. [14]
  Meiran Li , Yingjie Song , Xin Wan , Yang Li , Yiqi Luo , Yeheng He , Bowen Xia , Hua Zhou , Mingfei Shao . Nickel-Vanadium Layered Double Hydroxides for Efficient and Scalable Electrooxidation of 5-Hydroxymethylfurfural Coupled with Hydrogen Generation. Acta Physico-Chimica Sinica, 2024, 40(9): 2306007-0. doi: 10.3866/PKU.WHXB202306007
15. [15]
  Junjie TANG , Yunting ZHANG , Zhengjiang LIU , Jiani WU . Preparation of CeO₂ by starch template method for photo-Fenton degradation of methyl orange. Chinese Journal of Inorganic Chemistry, 2025, 41(8): 1617-1631. doi: 10.11862/CJIC.20240420
16. [16]
  Zongsheng LI , Yichao WANG , Yujie WANG , Wenhao ZHU , Xiaoyao YIN , Wudan YANG , Songzhi ZHENG , Weihai SUN . Preparation of CsPbBr₃ perovskite solar cells via bottom interface modification with methylammonium chloride. Chinese Journal of Inorganic Chemistry, 2025, 41(9): 1805-1816. doi: 10.11862/CJIC.20250066
17. [17]
  Yongjie ZHANG , Bintong HUANG , Yueming ZHAI . Research progress of formation mechanism and characterization techniques of protein corona on the surface of nanoparticles. Chinese Journal of Inorganic Chemistry, 2024, 40(12): 2318-2334. doi: 10.11862/CJIC.20240247
18. [18]
  Xinran Zhang , Siqi Liu , Yichi Chen , Qingli Zou , Qinghong Xu , Yaqin Huang . From Protein to Energy Storage Materials: Edible Gelatin Jelly Electrolyte. University Chemistry, 2025, 40(7): 255-266. doi: 10.12461/PKU.DXHX202408104
19. [19]
  Xiaoyang Li , Xiaowei Huang , Yimeng Zhang , Huan Liu , Shao Jin , Junpeng Zhuang . Comprehensive Chemical Experiments on the Synthesis of 1,3-Dibromo-5,5-Dimethylhydantoin and Its Application as a Brominating Reagent. University Chemistry, 2025, 40(7): 286-293. doi: 10.12461/PKU.DXHX202408035
20. [20]
  Junli Liu . Practice and Exploration of Research-Oriented Classroom Teaching in the Integration of Science and Education: a Case Study on the Synthesis of Sub-Nanometer Metal Oxide Materials and Their Application in Battery Energy Storage. University Chemistry, 2024, 39(10): 249-254. doi: 10.12461/PKU.DXHX202404023

Get Citation

PDF

XML

Metrics

PDF Downloads(1)
Abstract views(621)
HTML views(51)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Address：Zhongguancun North First Street 2,100190 Beijing, PR China Tel: +86-010-82449177-888

DownLoad: Full-Size Img PowerPoint

Return