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Citation: WANG Ran-Ran, LIANG Ping, XIE Zheng-Fenga, LIU Fang-Ming. Synthesis of 2-Phenyl-1,2,3-triazol-4-yl[1,2,4] Oxadiazolo[4,5-a][1,5] benzothiazepine Derivatives[J]. Chinese Journal of Applied Chemistry, ;2008, 25(12): 1389-1392. shu

Synthesis of 2-Phenyl-1,2,3-triazol-4-yl[1,2,4] Oxadiazolo[4,5-a][1,5] benzothiazepine Derivatives

1.
a Key Laboratory of Oil & Gas Fine Chemicals, Ministry of Education, Xinjiang University, Urumqi 830046;
2.
b College of Material, Chemistry and Chemical Engineering, Hangzhou Normal University, Hangzhou

Corresponding author: XIE Zheng-Fenga,
Received Date: 7 November 2007
Available Online: 28 January 2008
Fund Project: 国家自然科学基金(20562011) (20562011)

In the presence of triethylamine,the reaction of 2,4-disubstituted-2,3-dihydro-1,5-benzothia-zepine with α-chloro-2-phenyl-1,2,3-triazole-4-carbaldehyde oxime through 1,3-dipolar cycloadditon produces a series of 2-phenyl-1,2,3-triazol-4-yl[1,2,4] oxadiazolo[4,5-a][1,5] benzothiazepine derivatives.The compounds bearing benzothiazepine,1,2,3-triazole and 1,2,4-oxadiazole moieties may possess interesting bioactivities.
- cycloadditon reaction,
- oxime,
- benzothiazepine,
- synthesis
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