Citation: ZHANG Xue-Mei, OU Zhi-Bin, CHEN Shi, XIONG Ya-Hong, ZHOU Xiao-Hua, LIU Hai-Feng, LE Xue-Yi. Synthesis, Crystal Structure and DNA-Binding Properties of Copper(Ⅱ) Complex with 6-(Pyrazin-2′-yl)-1,3,5-triazine-2,4-diamine and Glycinate[J]. Chinese Journal of Inorganic Chemistry, ;2012, 28(12): 2667-2673. shu

Synthesis, Crystal Structure and DNA-Binding Properties of Copper(Ⅱ) Complex with 6-(Pyrazin-2′-yl)-1,3,5-triazine-2,4-diamine and Glycinate

1.
1. Department of Applied Chemistry, South China Agricultural University, Guangzhou 510642, China;

Corresponding author: LE Xue-Yi,
Received Date: 11 March 2012
Available Online: 8 July 2012
Fund Project: 广东省自然科学基金(No.10151064201000016) (No.10151064201000016)华南农业大学211工程重点项目(No.2009B010100001)资助项目. (No.2009B010100001)

The copper(Ⅱ) complex [Cu(H₂O)(Gly)(PZTA)]ClO₄ (Gly=glycinate) was prepared by the reaction of 6-(pyrazin-2′-yl)-1,3,5-triazine-2,4-diamine (PZTA) and glycine (Gly) with copper(Ⅱ) perchlorate, and characterized by elemental analysis, infrared radiation, UV-Vis, and molar conductance. Its crystal structure was determined by single crystal X-ray diffraction method. The complex crystallizes in the monoclinic system, space group C2/c, with cell parameters: a=2.189 6(3) nm, b=1.308 3(2) nm, c=1.465 4(4) nm, β=131.467(3)°, cell volume: V=3.145 6(9) nm³, number of molecules inside the cell: Z=8, final R indices (I>2σ(I)): R₁=0.037 4, wR₂=0.100 9. The interaction of the complex to DNA was studied by UV spectroscopy, EtBr fluoescent probe and viscosity measurement. The results indicate that the complex could interact with DNA by partial intercalative mode. CCDC: 848150.
- copper(Ⅱ) complex;6-(pyrazin-2′-yl)-1,3,5-triazine-2,4-diamine;glycine;crystal structure;DNA
1. [1]
  [1] Garoufis A, Hadjikakou S K, Hadjiliadis N. Coord. Chem. Rev., 2009,253(9-10):1384-1397
2. [2]
  [2] Patra A K, Roy S, Chakravarty A R. Inorg. Chim. Acta, 2009,362(13):4692-4698
3. [3]
  [3] Grueso E, López-Pérez G, Castellano M, et al. J. Inorg. Biochem., 2012,106(1):1-9
4. [4]
  [4] Bencini A, Lippolis V. Coord. Chem. Rev., 2010,254(17-18): 2096-2180
5. [5]
  [5] LU Yan-Mei(卢艳梅), LE Xue-Yi(乐学义). Chinese J. Inorg. Chem.(Wuji Huaxue Xuebao), 2011,27(2):199-213
6. [6]
  [6] Yoshikawa Y, Komeda S, Uemura M, et al. Inorg. Chem., 2011,50(22):11729-11735
7. [7]
  [7] Ren X X, Chen J Y, Le X Y. Chin. J. Chem., 2011,29(7): 1380-1388
8. [8]
  [8] Sasmal P K, Patra A K, Nesaji M, et al. Inorg. Chem., 2007, 46(26):11112-11121
9. [9]
  [9] HONG Xian-Lan(洪显兰), REN Jian-Min(任健敏). Chinese J. Inorg. Chem.(Wuji Huaxue Xuebao), 2011,27(4):785-790
10. [10]
  [10] BIAN Lin(边琳), LI Lian-Zhi(李连之), WANG Xia(王霞), et al. Chinese J. Inorg. Chem.(Wuji Huaxue Xuebao), 2011, 27(4):649-654
11. [11]
  [11] Reddy P R, Shilpa A, Raju N, et al. J. Inorg. Biochem., 2011,105(12):1603-1612
12. [12]
  [12] Bencini A, Lippolis V. Coord. Chem. Rev., 2010,254(17-18):2096-2180
13. [13]
  [13] The Chemical Society of Japanese, Translated by AN Jia-Ju (安家驹), Chen Zhi-Chuan(陈之川). Handbook of Inorganic Compounds Ⅱ(无机化合物手册,第2册). Beijing: Chemnistry Industry Press, 1986:513
14. [14]
  [14] Case F H. J. Heterocycl. Chem., 1968,5(2):223-226
15. [15]
  [15] Marmur J. J. Mol. Biol., 1961,3(1):208-218
16. [16]
  [16] Reichmann M E, Rice S A, Thomas C A, et al. J. Am. Chem. Soc., 1954,76(11):3047-3053
17. [17]
  [17] Blessing R. Acta Crystallog., 1995,A51:33
18. [18]
  [18] Sheldrick G M. SHELXL-97, Program for X-ray Crystal Structure Determination, Göttingen University, Germany, 1997.
19. [19]
  [19] Geary W J. Coord. Chem. Rev., 1971,7(1):81-122
20. [20]
  [20] LI Xiu-Mei(李秀梅), NIU Yang-Ling(牛艳玲), WANG Zhi-Tao(王志涛). Chinese J. Inorg. Chem.(Wuji Huaxue Xuebao), 2011,27(9):1837-1841
21. [21]
  [21] Subramanian P S, Suresh E, Dastidar P, et al. Inorg. Chem., 2001,40(17):4291-4301
22. [22]
  [22] Gu Q, Le X Y, Lin Q B, et al. J. Chin. Chem., 2007,25(6): 791-796
23. [23]
  [23] Le X Y, Gu Q, Song Z J, et al. J. Coord. Chem., 2007,60 (13):1359-1371
24. [24]
  [24] Zhang S C, Chun X G, Chen Y. J. Chin. Chem., 2011,29(1): 65-71
25. [25]
  [25] Wolf A, Jr Shimer G H, Meehan T. Biochemistry, 1987,26 (20):6392-6396
26. [26]
  [26] Chen J Y, Ren X X, Le X Y, et al. Chin. J. Chem., 2010,28 (11):2179-2187
27. [27]
  [27] Indumathy R, Radhika S, Kanthimathi M, et al. J. Inorg. Biochem., 2007,101(3):434-443
28. [28]
  [28] Lakowicz J R, Webber G. Biochemistry, 1973,12(21):4161-4170
29. [29]
  [29] Satyanarayana S, Dabrowiak J C, Chaires J B. Biochemistry, 1992,31(39):9319-9324
30. [30]
  [30] Liu F, Meadows K A, McMillin D R. J. Am. Chem. Soc., 1993,115(15):6699-6704
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