Citation: Maryam Saffari Jourshari, Manouchehr Mamaghani, Farhad Shirini, Khalil Tabatabaeian, Mehdi Rassa, Hadiss Langari. An expedient one-pot synthesis of highly substituted imidazoles using supported ionic liquid-like phase (SILLP) as a green and efficient catalyst and evaluation of their anti-microbial activity[J]. Chinese Chemical Letters, ;2013, 24(11): 993-996. shu

An expedient one-pot synthesis of highly substituted imidazoles using supported ionic liquid-like phase (SILLP) as a green and efficient catalyst and evaluation of their anti-microbial activity

a Department of Chemistry, Faculty of Sciences, University of Guilan, P.
a Department of Chemistry, Faculty of Sciences, University of Guilan, P.O. Box 41335-1914, Rasht, Iran;
b Department of Biology, Faculty of Sciences, University of Guilan, P.
b Department of Biology, Faculty of Sciences, University of Guilan, P.O. Box 41335-1914, Rasht, Iran

Corresponding author: Manouchehr Mamaghani,
Received Date: 7 April 2013
Available Online: 24 May 2013

An efficient method for the synthesis of imidazole derivatives by a three-component condensation of benzil or 9,10-phenanthrenequinone, aldehydes and ammonium acetate using supported ionic liquidlike phase (SILLP) catalyst under ultrasonic irradiation or classical heating conditions is reported. The present methodology offers several advantages, such as excellent yields, simple procedures, short reaction times, simple work-up and mild conditions. The catalyst is easily separated from the products by filtration and also exhibits remarkable reusable activity. These highly substituted imidazoles were also evaluated for their anti-microbial activity.
- SILLP,
- Imidazole,
- Phenanthroimidazole,
- Ionic liquid,
- Three-component reaction,
- Anti-microbial activities
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