Citation: Peng Guo, Jun-Hai Huang, Qing-Chun Huang, Xu-Hong Qian. Synthesis of novel 1,3-oxazole derivatives with insect growthinhibiting activities[J]. Chinese Chemical Letters, ;2013, 24(11): 957-961. shu

Synthesis of novel 1,3-oxazole derivatives with insect growthinhibiting activities

1.
Shanghai Key Laboratory of Chemical Biology, Institute of Pesticides and Pharmaceuticals, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China

Corresponding author: Xu-Hong Qian,
Received Date: 19 May 2013
Available Online: 13 June 2013

Straightforward and direct synthesis of 2-substituted-5-oxazolecarbaldehydes was achieved by treating propargylamides with mercury(Ⅱ) perchlorate as catalyst and ammonium cerium(Ⅳ) nitrate as oxidant agent through intramolecular cyclization. These structurally interesting outcomes benefit to synthesize 2,5-disubstituted-1,3-oxazoles with armyworm growth regulating activities.
- Oxazole,
- Mercury,
- Catalyst,
- Growth inhibiting activity
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沈阳化工大学材料科学与工程学院沈阳 110142