Citation: Liang Liu, Jun Li, Ke-Wu Zeng, Ping Li, Peng-Fei Tu. Three new phenanthrenes from Cremastra appendiculata (D. Don) Makino[J]. Chinese Chemical Letters, ;2013, 24(8): 737-739. shu

Three new phenanthrenes from Cremastra appendiculata (D. Don) Makino

Liang Liu ^a,b,c ,
Jun Li ^d ,
Ke-Wu Zeng ^b ,
Ping Li ^a ,
Peng-Fei Tu ^a,b,,

1.
a State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China;
2.
b State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China;
3.
c Medical College, Yangzhou University, Yangzhou 225009, China;
4.
d Modern Research Center for Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China

Corresponding author: Peng-Fei Tu,
Received Date: 5 February 2013
Available Online: 11 March 2013

Three new phenanthrenes, along with one known phenanthrene, were isolated from the ethanolic extract of the tubers of Cremastra appendiculata (D. Don) Makino. Their structures were elucidated on the basis of extensive spectroscopic analysis. Compounds 1-4 were tested for in vitro cytotoxic activities against human lung (A549), colon (HCT-116), liver (HepG2), and breast (MCF-7 and MDA-MB-231) cancer cell lines.
- Phenanthrene,
- Cremastra appendiculata,
- Chemical constituent,
- Cytotoxicity
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