Citation: Ke-Rang Wang, Hong-Wei An, Dan Han, Feng Qian, Xiao-Liu Li. Fluorescence quenching of triazatruxene-based glycocluster induced by peanut agglutinin lectin[J]. Chinese Chemical Letters, ;2013, 24(6): 467-470. shu

Fluorescence quenching of triazatruxene-based glycocluster induced by peanut agglutinin lectin

Ke-Rang Wang ^a,b,, ,
Hong-Wei An ^a,b ,
Dan Han ^a,b ,
Feng Qian ^a,b ,
Xiao-Liu Li ^a,b,,

1.
a Key Laboratory of Chemical Biology of Hebei Province, College of Chemistry and Environmental Science, Hebei University, Baoding 071002, China;
2.
b Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, Hebei University, Baoding 071002, China

Corresponding author: Ke-Rang Wang, Xiao-Liu Li,
Received Date: 5 February 2013
Available Online: 12 March 2013

A novel triazatruxene-based fluorescent glycocluster was synthesized and its selective binding interactions with PNA lectin were investigated by fluorescence spectroscopy, CD spectroscopy, and a turbidity assay. The glycocluster exhibited a strong binding affinity for PNA lectin with a Stern-Volmer quenching constant of 5.8×10⁵ mol^-1 L.
- Triazatruxene,
- Glycocluster,
- Fluorescence quenching,
- Peanut agglutinin
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