Citation: Zong-Hua Wang, Jian-Fei Xia, Fu-Yong Zhao, Qiang Han, Xin-Mei Guo, Hui Wang, Ming-Yu Ding. Determination of benzoic acid in milk by solid-phase extraction and ion chromatography with conductivity detection[J]. Chinese Chemical Letters, ;2013, 24(3): 243-245. shu

Determination of benzoic acid in milk by solid-phase extraction and ion chromatography with conductivity detection

1.
a Laboratory of Fiber Materials and Modern Textile, The Growing Base for State Key Laboratory, College of Chemical and Environment Engineering, Qingdao University, Qingdao 266071, China;
b Metrohm China Ltd.
b Metrohm China Ltd., Beijing 100005, China;
3.
c Beijing Key Laboratory for Microanalytical Methods and Instrumentation, Department of Chemistry, Tsinghua University, Beijing 100084, China

Corresponding author: Zong-Hua Wang,
Received Date: 8 November 2012
Available Online: 16 January 2013

A simple, fast, precise and eco-friendly method, based on ion chromatography (IC) with a suppressed conductivity detector, was proposed for the determination of benzoic acid (BA) inmilk in this paper. The chromatographic separation was accomplished by using an anion exchange column eluted with 3.2 μmol/L aqueous Na₂CO₃ and 1.0 mmol/L aqueous NaHCO₃ at a flow-rate of 0.7 mL/min. Themethod validation experiment provided excellent results with respect to linearity (correlation coefficient up to 0.9997), limit of detection (0.1 μg/L), recovery values (ranging from 88.0% to 93.0%) and relative standard deviation (RSD) (below 2.2%, n = 7).
- Ion chromatography,
- Benzoic acid,
- Solid-phase extraction,
- Milk
1. [1]
  [1] M.G. Soni, G.A. Burdock, S.L. Taylor, N.A. Greenberg, Safety assessment of propyl paraben: a review of the published literature, Food Chem. Toxicol. 39 (2001) 513-532.
2. [2]
  [2] P.D. Darbre, Underarm cosmetics and breast cancer, J. Appl. Toxicol. 23 (2003) 89-95.
3. [3]
  [3] European Parliament and Council Directive, No. 95/2/EC, February 1995.
4. [4]
  [4] C.Z. Dong, Y. Mei, L. Chen, Simultaneous determination of sorbic and benzoic acids in food dressing by headspace solid-phase microextraction and gas chromatography, J. Chromatogr. A 1117 (2006) 109-114.
5. [5]
  [5] Z.F. Pan, L.L. Wang, W.M. Mo, et al., Determination of benzoic acid in soft drinks by gas chromatography with on-line pyrolytic methylation technique, Anal. Chim. Acta 545 (2005) 218-223.
6. [6]
  [6] B. Saad, M.F. Bari, M.I. Saleh, K. Ahmad, M.K.M. Talib, Simultaneous determination of preservatives (benzoic acid, sorbic acid, methylparaben and propylparaben) in foodstuffs using high-performance liquid chromatography, J. Chromatogr. A 1073 (2005) 393-397.
7. [7]
  [7] K. Ma, Y.N. Yang, X.X. Jiang, M. Zhao, Y.Q. Cai, Simultaneous determination of 20 food additives by high performance liquid chromatography with photo-diode array detector, Chin. Chem. Lett. 23 (2012) 492-495.
8. [8]
  [8] I.M. Ferreir, E. Mendes, P. Brito, M.A. Ferreira, Simultaneous determination of benzoic and sorbic acids in quince jam by HPLC, Food Res. Int. 33 (2000) 113-117.
9. [9]
  [9] S.A.V. Tfouni, M.C.F. Toledo, Determination of benzoic and sorbic acids in Brazilian food, Food Control 13 (2002) 117-123.
10. [10]
  [10] C.Z. Dong, W.F. Wang, Headspace solid-phase microextraction applied to the simultaneousdetermination of sorbic and benzoic acids in beverages, Anal. Chim. Acta 562 (2006) 23-29.
11. [11]
  [11] N. Penner, R. Ramanathan, J. Zgoda-Pols, S. Chowdhury, Quantitative determination of hippuric and benzoic acids in urine by LC-MS/MS using surrogate standards, J. Pharm. Biomed. Anal. 52 (2010) 534-543.
12. [12]
  [12] F. Han, Y.Z. He, L. Li, et al., Determination of benzoic acid and sorbic acid in food products using electrokinetic flow analysis-ion pair solid phase extraction-capillary zone electrophoresis, Anal. Chim. Acta 618 (2008) 79-85.
13. [13]
  [13] X.F. Zhang, S.X. Xu, Y.H. Sun, Y.Y. Wang, C. Wang, Simultaneous determination of benzoic acid and sorbic acid in food products by CE after on-line preconcentration by dynamic pH junction, Chromatographia 73 (2011) 1217-2122.
1. [1]
  Shuangying Li , Qingxiang Zhou , Zhi Li , Menghua Liu , Yanhui Li . Sensitive measurement of silver ions in environmental water samples integrating magnetic ion-imprinted solid phase extraction and carbon dot fluorescent sensor. Chinese Chemical Letters, 2024, 35(5): 108693-. doi: 10.1016/j.cclet.2023.108693
2. [2]
  Ling Liu , Haibin Wang , Genrong Qiang . Curriculum Ideological and Political Design for the Comprehensive Preparation Experiment of Ethyl Benzoate Synthesized from Benzyl Alcohol. University Chemistry, 2024, 39(2): 94-98. doi: 10.3866/PKU.DXHX202304080
3. [3]
  Junjie Zhang , Yue Wang , Qiuhan Wu , Ruquan Shen , Han Liu , Xinhua Duan . Preparation and Selective Separation of Lightweight Magnetic Molecularly Imprinted Polymers for Trace Tetracycline Detection in Milk. University Chemistry, 2024, 39(5): 251-257. doi: 10.3866/PKU.DXHX202311084
4. [4]
  Cheng Guo , Xiaoxiao Zhang , Xiujuan Hong , Yiqiu Hu , Lingna Mao , Kezhi Jiang . Graphene as adsorbent for highly efficient extraction of modified nucleosides in urine prior to liquid chromatography-tandem mass spectrometry analysis. Chinese Chemical Letters, 2024, 35(4): 108867-. doi: 10.1016/j.cclet.2023.108867
5. [5]
  Wangyan Hu , Ke Li , Xiangnan Dou , Ning Li , Xiayan Wang . Nano-sized stationary phase packings retained by single-particle frit for microchip liquid chromatography. Chinese Chemical Letters, 2024, 35(4): 108806-. doi: 10.1016/j.cclet.2023.108806
6. [6]
  Tong Zhang , Xiaojing Liang , Licheng Wang , Shuai Wang , Xiaoxiao Liu , Yong Guo . An ionic liquid assisted hydrogel functionalized silica stationary phase for mixed-mode liquid chromatography. Chinese Chemical Letters, 2025, 36(1): 109889-. doi: 10.1016/j.cclet.2024.109889
7. [7]
  Linshan Peng , Qihang Peng , Tianxiang Jin , Zhirong Liu , Yong Qian . Highly efficient capture of thorium ion by citric acid-modified chitosan gels from aqueous solution. Chinese Chemical Letters, 2024, 35(5): 108891-. doi: 10.1016/j.cclet.2023.108891
8. [8]
  Shiyu Pan , Bo Cao , Deling Yuan , Tifeng Jiao , Qingrui Zhang , Shoufeng Tang . Complexes of cupric ion and tartaric acid enhanced calcium peroxide Fenton-like reaction for metronidazole degradation. Chinese Chemical Letters, 2024, 35(7): 109185-. doi: 10.1016/j.cclet.2023.109185
9. [9]
  Jia-hui Li , Jinkai Qiu , Cheng Lian . Lithium-ion rapid transport mechanism and channel design in solid electrolytes. Chinese Journal of Structural Chemistry, 2025, 44(1): 100381-100381. doi: 10.1016/j.cjsc.2024.100381
10. [10]
  Shengyu Zhao , Qinhao Shi , Wuliang Feng , Yang Liu , Xinxin Yang , Xingli Zou , Xionggang Lu , Yufeng Zhao . Suppression of multistep phase transitions of O3-type cathode for sodium-ion batteries. Chinese Chemical Letters, 2024, 35(5): 108606-. doi: 10.1016/j.cclet.2023.108606
11. [11]
  Ying Li , Yanjun Xu , Xingqi Han , Di Han , Xuesong Wu , Xinlong Wang , Zhongmin Su . A new metal–organic rotaxane framework for enhanced ion conductivity of solid-state electrolyte in lithium-metal batteries. Chinese Chemical Letters, 2024, 35(9): 109189-. doi: 10.1016/j.cclet.2023.109189
12. [12]
  Zhihong LUO , Yan SHI , Jinyu AN , Deyi ZHENG , Long LI , Quansheng OUYANG , Bin SHI , Jiaojing SHAO . Two-dimensional silica-modified polyethylene oxide solid polymer electrolyte to enhance the performance of lithium-ion batteries. Chinese Journal of Inorganic Chemistry, 2024, 40(5): 1005-1014. doi: 10.11862/CJIC.20230444
13. [13]
  Qian Wang , Ting Gao , Xiwen Lu , Hangchao Wang , Minggui Xu , Longtao Ren , Zheng Chang , Wen Liu . Nanophase separated, grafted alternate copolymer styrene-maleic anhydride as an efficient room temperature solid state lithium ion conductor. Chinese Chemical Letters, 2024, 35(7): 108887-. doi: 10.1016/j.cclet.2023.108887
14. [14]
  Linhui Liu , Wuwan Xiong , Mingli Fu , Junliang Wu , Zhenguo Li , Daiqi Ye , Peirong Chen . Efficient NO_x abatement by passive adsorption over a Pd-SAPO-34 catalyst prepared by solid-state ion exchange. Chinese Chemical Letters, 2024, 35(4): 108870-. doi: 10.1016/j.cclet.2023.108870
15. [15]
  Yue Zheng , Tianpeng Huang , Pengxian Han , Jun Ma , Guanglei Cui . Cathodal Li-ion interfacial transport in sulfide-based all-solid-state batteries: Challenges and improvement strategies. Chinese Journal of Structural Chemistry, 2024, 43(10): 100390-100390. doi: 10.1016/j.cjsc.2024.100390
16. [16]
  Xin Li , Ling Zhang , Yunyan Fan , Shaojing Lin , Yong Lin , Yongsheng Ying , Meijiao Hu , Haiying Gao , Xianri Xu , Zhongbiao Xia , Xinchuan Lin , Junjie Lu , Xiang Han . Carbon interconnected microsized Si film toward high energy room temperature solid-state lithium-ion batteries. Chinese Chemical Letters, 2025, 36(2): 109776-. doi: 10.1016/j.cclet.2024.109776
17. [17]
  Tian Feng , Yun-Ling Gao , Di Hu , Ke-Yu Yuan , Shu-Yi Gu , Yao-Hua Gu , Si-Yu Yu , Jun Xiong , Yu-Qi Feng , Jie Wang , Bi-Feng Yuan . Chronic sleep deprivation induces alterations in DNA and RNA modifications by liquid chromatography-mass spectrometry analysis. Chinese Chemical Letters, 2024, 35(8): 109259-. doi: 10.1016/j.cclet.2023.109259
18. [18]
  Feng-Qing Huang , Yu Wang , Ji-Wen Wang , Dai Yang , Shi-Lei Wang , Yuan-Ming Fan , Raphael N. Alolga , Lian-Wen Qi . Chemical isotope labeling-assisted liquid chromatography-mass spectrometry enables sensitive and accurate determination of dipeptides and tripeptides in complex biological samples. Chinese Chemical Letters, 2024, 35(11): 109670-. doi: 10.1016/j.cclet.2024.109670
19. [19]
  Wenyi Mei , Lijuan Xie , Xiaodong Zhang , Cunjian Shi , Fengzhi Wang , Qiqi Fu , Zhenjiang Zhao , Honglin Li , Yufang Xu , Zhuo Chen . Design, synthesis and biological evaluation of fluorescent derivatives of ursolic acid in living cells. Chinese Chemical Letters, 2024, 35(5): 108825-. doi: 10.1016/j.cclet.2023.108825
20. [20]
  Huipeng Zhao , Xiaoqiang Du . Polyoxometalates as the redox anolyte for efficient conversion of biomass to formic acid. Chinese Journal of Structural Chemistry, 2024, 43(2): 100246-100246. doi: 10.1016/j.cjsc.2024.100246

Get Citation

PDF

XML

Metrics

PDF Downloads(0)
Abstract views(663)
HTML views(1)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142