Citation: Shu Jie HOU, Peng XU, Liang ZHOU, De Quan YU, Ping Sheng LEI, Chuan Chun ZOU. Total Synthesis of the Analogue of Icogenin[J]. Chinese Chemical Letters, ;2006, 17(2): 183-186. shu

Total Synthesis of the Analogue of Icogenin

Shu Jie HOU ^1,2, ,
Peng XU ^1,2 ,
Liang ZHOU ^1,2 ,
De Quan YU ^1,2 ,
Ping Sheng LEI ^1,2 ,
Chuan Chun ZOU ²

1.
Key Laboratory of Bioactive Substance and Resources Utilization of Chinese Herbal Medicine(Peking Union Medical College), Ministry of Education;
2.
Institute of Materia Medica, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing 100050

Received Date: 27 June 2005

Fund Project: Financial support of this research by the National Natural Science Foundation of China (No. 20372085) is gratefully acknowledged.

One of the analogues of icogenin, a natural furostanol saponin showing strong cytotoxic effect on cancer cell, was first synthesized via convergent strategy by using diosgenin and available monosaccharides as starting materials.
- Furostan saponin,
- icogenin,
- glycosylation,
- kyptogenin
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