Citation: Hua Liang JIANG, Kai Xian CHEN, Yun TANG, Jian Zhong CHEN, Ying LI, Qing Mi Wang, Quan LI, Ru Yun JI, Qian Kun ZHUANG. CYCLIC VOLTAMMETRY STUDY ON ANTIMALARIAL MECHANISM OF ARTEMISININ (QINGHAOSU) DERIVATIVES[J]. Chinese Chemical Letters, ;1996, 7(7): 623-626. shu

CYCLIC VOLTAMMETRY STUDY ON ANTIMALARIAL MECHANISM OF ARTEMISININ (QINGHAOSU) DERIVATIVES

a Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 294 Taiyuan Road, Shanghai 200031;
b Department of Chemistry, Peking University, Beijing 100871

Received Date: 5 December 1995

Cyclic voltammetry method was used to determine the cyclic voltammogram of artemisinin derivatives and reduction potentials (RPs) of these compounds were obtained. Combining the determination results of Zhang and co-workers, QSAR analysis was performed between the activity and reduction potentials (RPs), which illustrated the antimalarial mechanism of artemisinin analogs. The experimental result verified and tested our previous theoretical calculation results.
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