Citation: Kang Tat REN, Hut Ying LI, Jun QI, Hong Hai SONG, Xiang WANG, Hua Zheng YANG. A Novel Nucleophilic Substitution of 3-Halo-6-phenoxypyridazines[J]. Chinese Chemical Letters, ;1999, 10(1): 13-14. shu

A Novel Nucleophilic Substitution of 3-Halo-6-phenoxypyridazines

Institute of Elemento-Organic Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Tianjin, 300071

Received Date: 24 August 1998

A novel nucleophilic substitution of pyridazines is found, in which phenoxy group is dislodged rather than the halogen atom, on treating 3-haIo-6-phenoxypyridazines with alkoxy anion. The reactivity of substituents on benzene ring and the halogen atom of pyridazines are studied. Reasonable explanation based on the quantum chemical calculations are given.
- Nucleophilic substitution,
- 3-halo-6-phenoxypyridazines,
- mechanisms
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