Citation: Li Jian LIU, Shao Hua SHI, Ren Xi ZHUO, Zheng Rong LU. Preparation of Dendrimers from Macromolecular Cores and Papain Immobilization[J]. Chinese Chemical Letters, ;1998, 9(3): 263-264. shu

Preparation of Dendrimers from Macromolecular Cores and Papain Immobilization

Department of Chemistry, Wuhan University, Laboratory of Biomedical Polymer Materials of the State Education Commission of China Wuhan 430072

Received Date: 24 November 1997

Using amino-poly(ethylene glycol) and amino-propyl silica gel as initiator cores, two dendrimers were prepared by a two-step procedure. The progress of dendrimers during each step was monitored by infrared spectroscopy and elemental analysis. Papain was crosslinked to the solid dendrimer with silica gel core by glutaraldehyde, and the enzymatic activity of the immobilized papain kept almost unchanged after repeated usage for fifteen times.
- Amino-poly (ethylene glycol),
- Amino-propyl silica gel,
- Dendrimer,
- Immobilized papain
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