Citation: Wen Han LIN, Jun LI, Hong Zheng FU, Peter PROKSCH. Four Novel Hydropyranoindeno-Derivatives from Marine Fungus Aspergillus versicolor[J]. Chinese Chemical Letters, ;2001, 12(5): 435-438. shu

Four Novel Hydropyranoindeno-Derivatives from Marine Fungus Aspergillus versicolor

1.
National Research Laboratories of Natural and Biomimetic Drugs, Peking University, Beijing 100083;
2.
Institut fuer Pharmazeutische Biologie, Heinrich-Heine Universitat, Duesseldorf D-40225

Received Date: 8 October 2000

Fund Project: This project is supported by NNSF of China (No.29932030).

From the cultured filtrates of fungus Aspergillus versicolor,isolated from marine sponge Xestospongia exigua,four novel secondary metabolites,namely aspergillone 1,aspergillodiol 2, aspergillol 3 and 12-acetyl-aspergillol 4,have been isolated by column chromatographic separation.The structures of all the new compounds are established on the basis of extensive 2D NMR spectroscopy in conjugation with MS,UV spectral analysis.The basic structure pattern of those compounds possessed an hydroindenoisopyran nucleus.
- Aspergillus versicolor,
- aspergillone,
- aspergillodiol,
- aspergillol,
- 12-acetyl-aspergillol.
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