Citation: Ju Mingjie, Xu Binbin, Xu Ligong. Synthesis and Properties of Blood Compatible Polyurethane Elastomer[J]. Chinese Journal of Organic Chemistry, ;2020, 40(12): 4344-4349. doi: 10.6023/cjoc202006004 shu

Synthesis and Properties of Blood Compatible Polyurethane Elastomer

Ju Mingjie ^a ,
Xu Binbin ^b,, ,
Xu Ligong ^a,,

a.
School of Sports Science and Engineering, East China University of Science and Technology, Shanghai 200237
b.
School of Materials Science and Engineering, East China University of Science and Technology, Shanghai 200237

Corresponding author: Xu Binbin, binbinxu@ecust.edu.cn Xu Ligong, xuligong@ecust.edu.cn
Received Date: 4 June 2020
Revised Date: 16 June 2020
Available Online: 5 August 2020
Fund Project: National Natural Science Foundation of China 22001072Shanghai Sailing Program 19YF1410300Project supported by National Natural Science Foundation of China (No. 22001072), and Shanghai Sailing Program (No. 19YF1410300)

Figures(6)

Polyurethane materials are widely used in biomedical fields such as implantable catheters and drug delivery. However, their blood compatibility is difficult to meet the rigorous requirements needed for a new generation of biomedical devices. A series of polyurethane elastomers were prepared using polycarbonate diols (PC), polyoxytertramethylene glycol (PTMG), isophorone diisocyanate (IPDI) and chain extender (BDO, E-300) as raw materials. The properties of polyurethane elastomers were investigated by FT-IR spectrum, differential scanning calorimeter (DSC) analysis, mechanical test, water contact angle measurement, hemolysis and cell compatibility test. The mechanical results show that the materials have superior tensile strength and elongation, meanwhile, the homolysis and cells compatibility tests exhibit that they have good bio-compatibility. In addition, the materials can achieve the best performance by using IPDI as well as chain extender E-300 as the hard segment and PC as the soft segment.
- polyurethane,
- elastomer,
- hemolysis,
- blood compatibility
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