Citation: Mei Huihui, Yang Mingyang, Liu Xiaoyan, Tian Yuping, Xu Kuoxi. A Novel Phenanthroline-Based Fluorescent Probe for Pb(Ⅱ)[J]. Chinese Journal of Organic Chemistry, ;2020, 40(8): 2508-2512. doi: 10.6023/cjoc202004037 shu

A Novel Phenanthroline-Based Fluorescent Probe for Pb(Ⅱ)

a.
College of Chemistry and Chemical Engineering, Henan University, Kaifeng, Henan 475004
b.
Mingsheng College, Henan University, Kaifeng, Henan 475004

Corresponding author: Tian Yuping, tianyuping@henu.edu.cn Xu Kuoxi, xukx@henu.edu.cn
Received Date: 24 April 2020
Revised Date: 17 May 2020
Available Online: 29 May 2020
Fund Project: Project supported by the Natural National Science Foundation of China (No. 31872311)The Natural National Science Foundation of China 31872311

Figures(4)

A novel fluorescent probe L for Pb²⁺ based phenanthroline derivative has been designed and synthesized. The probe L displayed fluorescence quenching emission excellent sensitivity specific toward Pb²⁺ ion. The introduction of Pb²⁺ resulted the quenching fluorescence of probe L and the color of the solution can be observed changes from yellow to orange in DMF-H₂O (V:V=1:1, 10 mmol/L Tris, pH=7.4). The detection limit was as low as 2.68×10^-7 mol/L. The bonding mechanism was confirmed by UV-vis, fluorescence, HRMS, ¹H NMR experiments and theoretical calculation. It was found that the probe had excellent reversibility for detection of Pb²⁺ and could be used to effectively identify Pb²⁺ in living cells.
- phenanthroline derivative,
- fluorescent probe for Pb²⁺,
- living cell imaging
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