Citation: Yang Liu, Xu Guohe, Ma Jingjun, Yang Qian, Feng An, Cui Jinggang. Recent Advances in the Application of in-situ Generated Hypervalent Iodine Reagents in Organic Synthesis[J]. Chinese Journal of Organic Chemistry, ;2020, 40(1): 28-39. doi: 10.6023/cjoc201906023 shu

Recent Advances in the Application of in-situ Generated Hypervalent Iodine Reagents in Organic Synthesis

Yang Liu ^a ,
Xu Guohe ^a ,
Ma Jingjun ^a,, ,
Yang Qian ^b ,
Feng An ^a ,
Cui Jinggang ^a

a.
College of Science & Technoloy, Agricultural University of Hebei Bohai Campus, Huanghua, Hebei 061100
b.
College of Veterinary Medicine, Hebei Agricultural University, Baoding, Hebei 071001

Corresponding author: Ma Jingjun, mjjwjpmartin@163.com
Received Date: 19 June 2019
Revised Date: 27 August 2019
Available Online: 13 January 2019
Fund Project: Project supported by the Young Tip-Top Talents Plan of Universities and Colleges in Hebei Province (No. BJ201702), and the Specific Foundation for Doctor in Hebei Agriculture University of China (No. ZD2016027)the Specific Foundation for Doctor in Hebei Agriculture University of China ZD2016027the Young Tip-Top Talents Plan of Universities and Colleges in Hebei Province BJ201702

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Based on the atomic economy, mild performance and environment friendly, the in-situ generation of hypervalent iodine reagents has been vastly applied in many significant oxidative reactions and asymmetric catalysis. In this paper, the progress of in-situ generated hypervalent iodine reagents is systematically reviewed, including conception and mechanisms. According to the different reaction types, the application of in-situ generated hapervalent iodine reagent in organic synthesis reaction is summarized, including trivalent iodine reagent, pentavalent iodine reagent and chiral hypervalent iodine reagent. The problem of in-situ generated hapervalent iodine researches is analyzed, and the future development of in-situ hapervalent iodine is prospected.
- in-situ generation,
- hypervalent iodine reagent,
- organic synthesis
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