Citation: Li Pengfei, Huang Danfeng, Yang Tianyu, Deng Zhoubin, Wang Kehu, Wang Junjiao, Su Yingpeng, Hu Yulai. Synthesis of Pyrazolines by Cascade Oxidation/Halogenoamino-cyclization Reaction of Homoallylhydrazides[J]. Chinese Journal of Organic Chemistry, ;2019, 39(10): 2920-2929. doi: 10.6023/cjoc201903073 shu

Synthesis of Pyrazolines by Cascade Oxidation/Halogenoamino-cyclization Reaction of Homoallylhydrazides

College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070

Corresponding author: Hu Yulai, huyl@nwnu.edu.cn
Received Date: 29 March 2019
Revised Date: 26 April 2019
Available Online: 21 October 2019
Fund Project: Project supported by the National Natural Science Foundation of China (Nos. 21662030, 21861033)the National Natural Science Foundation of China 21861033the National Natural Science Foundation of China 21662030

Figures(1)

An efficient cascade oxidation/halogenoaminocyclization reaction of homoallylhydrazides with N-halogensuc-cinimide was developed without addition of other additives under mild reaction conditions to provide pyrazolines. Under the optimized conditions, a variety of highly substituted pyrazoline derivatives were obtained.
- oxidation/halogenoaminocyclization,
- pyrazolines,
- homoallylhydrazides,
- N-halogensuccinimide
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