Citation: Wu Mei, Huang Xinping, Zhang Haibing, Li Pengfei. Advances on Directing-Group Assisted meta-C-H Functionalization Catalyzed by Transition Metal[J]. Chinese Journal of Organic Chemistry, ;2019, 39(11): 3114-3131. doi: 10.6023/cjoc201903029 shu

Advances on Directing-Group Assisted meta-C-H Functionalization Catalyzed by Transition Metal

a.
State Key Laboratory of Heavy Oil Processing, China University of Petroleum-Beijing At Karamay, Karamay, Xingjiang 834000
b.
Petrochina Karamay Petrochemical CO. LTD, Karamay, Xingjiang 834000

Corresponding author: Wu Mei, wumei_1121@163.com
Received Date: 15 March 2019
Revised Date: 31 May 2019
Available Online: 19 November 2019
Fund Project: Project supported by the Science Foundation of China University of Petroleum-Beijing at Karamay (No. RCYJ2016B-03-003)the Science Foundation of China University of Petroleum-Beijing at Karamay RCYJ2016B-03-003

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Transition-metal-catalyzed functionalization of unactivated C-H bonds is a highly attractive strategy for the synthesis of organic molecules, however, regioselective control is a central challenge in this field. The directing group assisted C-H functionalizations such as the use of directing templates and transient mediator, secondary interaction have attracted more attentions from researchers. The meta-C-H functionalizatioin assisted by directing groups are summarized in details. The existing problems and limitations of this field are also included. Finally, the development trend of this area is prospected.
- directed by template,
- meta-activation,
- C-H functionalization,
- secondary interaction,
- transient mediator
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