Citation: Zhang Huaiyuan, Tang Rongping, Shi Xingli, Xie Lin, Wu Jiawei. Recent Advances in Organic Electrochemical Synthesis and Application of Hypervalent Iodine Reagents[J]. Chinese Journal of Organic Chemistry, ;2019, 39(7): 1837-1845. doi: 10.6023/cjoc201902006 shu

Recent Advances in Organic Electrochemical Synthesis and Application of Hypervalent Iodine Reagents

Gansu Province Collaborative Innovation Center of Petrochemical Engineering Application Technology, College of Applied Chemical Engineering, Lanzhou Petrochemical Polytechnic, Lanzhou 730060

Corresponding author: Zhang Huaiyuan, zhanghuaiyuan@lzpcc.edu.cn
Received Date: 11 February 2019
Revised Date: 10 March 2019
Available Online: 9 July 2019
Fund Project: the Scientific Research Projects of Colleges and Universities in Gansu Province 2018B-091Project supported by the Scientific Research Projects of Colleges and Universities in Gansu Province (No. 2018B-091) and the Teaching and Scientific Research Project of Lanzhou Petrochemical Poly Technic (No. JY2018-25)the Teaching and Scientific Research Project of Lanzhou Petrochemical Poly Technic JY2018-25

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Anodic oxidation of aryl iodine compouds is a green and efficient method for the synthesis of hypervalent iodine reagents. This method replaces chemical reagents with electric current, avoiding the use of expensive and handle difficult oxidants such as m-CPBA, H₂O₂, oxone, selectfluor etc. Electrochemically generated hypervalent iodine reagents can not only promote fluorination, oxidative cyclization, but also be successfully applied in the total synthesis of natural products. In addition, recyclable aryl iodine mediator can be used to indirect anodic fluorination and easily separated from products. The organic electrochemical synthesis of hypervalent iodine reagents and their applications in various chemical transformations are reviewed.
- electrochemical synthesis,
- hypervalent iodine reagent,
- fluorination,
- oxidative cyclization
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