Citation: Yang Ziqi, Liu Xingkun, Jiang Lu'nan, Wang Mei. Design, Synthesis and Application of Fluorescence Resonance Energy Transfer-Based Ratiometric Hydrazine Fluorescent Probe[J]. Chinese Journal of Organic Chemistry, ;2019, 39(5): 1483-1488. doi: 10.6023/cjoc201811034 shu

Design, Synthesis and Application of Fluorescence Resonance Energy Transfer-Based Ratiometric Hydrazine Fluorescent Probe

a.
College of Chemistry and Environmental Science, Hebei University, Baoding 071002
b.
College of Pharmacy, Hebei University, Baoding 071002

Corresponding author: Wang Mei, wangmarian@163.com
Received Date: 28 November 2018
Revised Date: 7 January 2019
Available Online: 18 May 2019
Fund Project: the Science Technology Research and Development Guidance Programme Project of Baoding City 16zg031the Natural Science Foundation of Hebei Provience 2018201234the Science Technology Research and Development Guidance Programme Project of Baoding City 18ZF315Project supported by the National Natural Scinec Foundation of China (No. 51578067), the Natural Science Foundation of Hebei Provience (No. 2018201234), the Colleges and Universities Science Technology Research Project of Hebei Province (No. QN2017015) and the Science Technology Research and Development Guidance Programme Project of Baoding City (Nos. 16zg031, 18ZF315)the Colleges and Universities Science Technology Research Project of Hebei Province QN2017015the National Natural Scinec Foundation of China 51578067

Figures(6)

Hydrazine (N₂H₄) is a highly toxic biochemical reagent with the capability of mutagenic, teratogenic and carcinogenic. For accurately monitoring the concentration of N₂H₄ in the environment and life, two FRET (fluorescence resonance energy transfer)-based dual-emissive ratiometric fluorescent probes (FRET-1/2) were designed and synthesized. The structures of both probes were charactered by ¹H NMR, ¹³C NMR and HRMS. The results prove that both probes exhibit good selectivity and sensitivity to N₂H₄ and can be used for detecting N₂H₄ in water samples.
- hydrazine,
- fluorescence resonance energy transfer (FRET),
- ratiometric,
- fluorescent probe
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