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Citation: Yang Wencheng, Qi Xiaoxu, Chen Pinhong, Liu Guosheng. Palladium-Catalyzed Intramolecular Fluoroarylation of Alkenes[J]. Chinese Journal of Organic Chemistry, ;2019, 39(1): 122-128. doi: 10.6023/cjoc201810026 shu

Palladium-Catalyzed Intramolecular Fluoroarylation of Alkenes

  • State Key Laboratory of Organometallic Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032

  • Corresponding author: Chen Pinhong, pinhongchen@sioc.ac.cn Liu Guosheng, gliu@mail.sioc.ac.cn
  • Received Date: 20 October 2018
    Revised Date: 3 December 2018
    Available Online: 5 January 2018

    Fund Project: Project supported by he National Key R & D Program of China (973 Program, No. 2015CB856600), the National Natural Science Foundation of China (Nos. 21532009, 21672236, 21761142010, 21790330) and the Science Technology Commission of the Shanghai Municipality (Nos. 17QA1405200, 17JC1401200), and the Chinese Academy Sciences (Nos. XDB20000000, QYZDJSSW-SLH055) and the Youth Innovation Promotion Association (No.2018292)the Science Technology Commission of the Shanghai Municipality 17QA1405200the National Natural Science Foundation of China 21790330the National Natural Science Foundation of China 21532009the National Natural Science Foundation of China 21672236the Science Technology Commission of the Shanghai Municipality 17JC1401200the Chinese Academy Sciences QYZDJSSW-SLH055the Chinese Academy Sciences XDB20000000the Youth Innovation Promotion Association 2018292the National Natural Science Foundation of China 21761142010he National Key R & D Program of China (973 Program) 2015CB856600

Figures(3)

  • A novel palladium-catalyzed intramolecular fluoroarylation of alkenes has been developed, in which ArIF2 was employed as fluorine source as well as Ⅰ(Ⅲ) reagent to activate olefin, to deliver the fluoroarylation products from 4-aryl- 1-olefins in moderate to good yields. The current transformation presents a convenient method to provide fluorotetralins and fluorochromanes under mild conditions from alkenes tethered arenes.
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