Citation: Zhang Ruize, Wang Guodong, Li Hongshuang, Duan Guiyun, Wang Kai, Xia Chengcai. Strong-Acid Cation Exchange Resin Catalyzed Synthesis of Bis(indolyl)methanes in Water[J]. Chinese Journal of Organic Chemistry, ;2019, 39(5): 1429-1435. doi: 10.6023/cjoc201810011 shu

Strong-Acid Cation Exchange Resin Catalyzed Synthesis of Bis(indolyl)methanes in Water

a.
Pharmacy College, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai'an 271016
b.
Institute of Pharmacology, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai'an 271016

Corresponding author: Xia Chengcai, xiachc@163.com
Received Date: 11 October 2018
Revised Date: 18 December 2018
Available Online: 18 May 2019
Fund Project: the Medical and Health Technology Development Program in Shandong Province 2015WS0102Project supported by the Medical and Health Technology Development Program in Shandong Province (No. 2015WS0102)

Figures(2)

An efficient protocol for conversion of aldehyde and indole into bis(indolyl)methanes derivatives catalyzed by strong-acid cation exchange resin has been developed. The H₂O was used as solution and recycle catalyst can be used six times. Various bis(indolyl)methanes derivatives were obtained in excellent yields.
- strong-acid cation exchange resin,
- indole,
- bis(indolyl)methanes,
- condensation
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