Citation: Yang Ying, Balati Hasimujiang, Abulikemu Abudu Rexit. Research on Reduction of α, α, α-Tribromomethyl Ketones via Thiophenol[J]. Chinese Journal of Organic Chemistry, ;2019, 39(3): 727-733. doi: 10.6023/cjoc201810003 shu

Research on Reduction of α, α, α-Tribromomethyl Ketones via Thiophenol

Department of Chemistry, Xinjiang Normal University, Urumqi 830054

Corresponding author: Abulikemu Abudu Rexit, aarexit@xjnu.edu.cn
Received Date: 5 October 2018
Revised Date: 7 November 2018
Available Online: 25 March 2018
Fund Project: the National Natural Science Foundation of China 21662035Project supported by the National Natural Science Foundation of China (No. 21662035)

Figures(2)

α, α-Dibromomethyl ketones were synthesized with high yields through a thiophenol-promoted reduction of α, α, α-tribromomethyl ketones under mild conditions within one hour. A further mechanistic study showed that the reaction proceeded via a radical process. This is an example that uses thiophenol as the radical stimulator in the reduction of multi-halogenated compounds.
- thiophenol,
- α, α-dibromomethyl ketones,
- green synthesis,
- reduction
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