Citation: Zhao Xinyu, Ding Yangyang, Lü Yingtao, Kang Congmin. Research Progress on Green Synthesis of Imidazo[1, 2-a]pyridine Compounds[J]. Chinese Journal of Organic Chemistry, ;2019, 39(5): 1304-1315. doi: 10.6023/cjoc201809034 shu

Research Progress on Green Synthesis of Imidazo[1, 2-a]pyridine Compounds

a.
College of Chemical Engineering, Qingdao University of Science and Technology, Shandong Province, Qingdao 266042
b.
Ocean College, Qingdao University of Science and Technology, Shandong Province, Qingdao 266042

Corresponding author: Kang Congmin, qustndds@163.com
Received Date: 27 September 2018
Revised Date: 24 November 2018
Available Online: 9 May 2019
Fund Project: Project supported by the Key Laboratory of Marine Bioactive Substance and Modern Analytical Technique (No. MBSMAT-2017-06)the Key Laboratory of Marine Bioactive Substance and Modern Analytical Technique MBSMAT-2017-06

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Imidazo[1, 2-a]pyridine compounds were 5- and 6-membered nitrogen heterocyclic compounds, which were found in various natural products and exhibited a wide range of pharmacological activities, and were widely used in medical chemistry. Imidazo[1, 2-a]pyridines have important research significance and broad medical application prospects, so the synthetic strategy literatures on the diversity of such compounds have been continuously reported. In recent years, green chemistry was one of the hot trends in contemporary chemistry. More and more attention is paid to green synthesis and constantly developing various green synthesis solutions. Among them, one-pot "multi-component" reaction, microwave reaction and solid phase synthesis, which were green and high-efficiency synthetic methods, have been the focus of research. From the three types of green synthesis methods, The research progress of imidazole[1, 2-a]pyridine green synthesis in recent years is summarized.
- green synthesis,
- one pot "multi-component reaction",
- microwave reaction,
- solid phase synthesis
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1.
沈阳化工大学材料科学与工程学院沈阳 110142