Citation: Feng Chunlai, Zhu Jie, Tang Qiujie, Zhou Aihua. Synthesis of ArSe-Substituted Flavone Derivatives Using Se Powder[J]. Chinese Journal of Organic Chemistry, ;2019, 39(4): 1187-1192. doi: 10.6023/cjoc201808011 shu

Synthesis of ArSe-Substituted Flavone Derivatives Using Se Powder

Pharmacy School, Jiangsu University, Zhenjiang 212013

Corresponding author: Zhou Aihua, ahz@ujs.edn.cn
Received Date: 10 August 2018
Revised Date: 20 September 2018
Available Online: 11 April 2018
Fund Project: Jiangsu University 1281290006Project supported by Jiangsu University (No. 1281290006)

Figures(2)

New flavone derivatives are highly valued in drug discovery due to their diversity of important bioactivities. Herein, one simple Cu-catalyzed method of constructing C-Se bonds on flavone structures using convenient Se powder via C-H functionalization is reported, regioselectively affording ArSe-substituted flavone derivatives in good yields.
- selenium,
- C—Se bond,
- flavone,
- selenide,
- C—H functionalization
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