Citation: Huang Jin, Fu Ronghui, Jing Linhai, Qin Dabin, Huang Kun, Wang Wei. A Convenient Access to 3-Substituted Benzofuran Derivatives via Palladium Nanoparticles-Catalyzed Intramolecular Heck Reaction[J]. Chinese Journal of Organic Chemistry, ;2019, 39(2): 456-462. doi: 10.6023/cjoc201807040 shu

A Convenient Access to 3-Substituted Benzofuran Derivatives via Palladium Nanoparticles-Catalyzed Intramolecular Heck Reaction

Chemical Synthesis Pollution Control Key Laboratory of Sichuan Province, Institute of Applied Chemistry, College of Chemistry and Chemical Engineering, China West Normal University, Nanchong 637002

Corresponding author: Wang Wei, wangwei1987@cwnu.edu.cn
Received Date: 23 July 2018
Revised Date: 29 August 2018
Available Online: 17 February 2018
Fund Project: the Science and Technology Program of Sichuan Province 2018JY0485the National Natural Science Foundation of China 21602144Project supported by the National Natural Science Foundation of China (No. 21602144), and the Science and Technology Program of Sichuan Province (No. 2018JY0485)

Figures(2)

A concise and efficiently route for the synthesis of 3-substituted benzofurans via the intramolecular Heck reaction of bromoaryl 3-phenylallyl ethers has been developed. This simple and highly efficient palladium nanoparticles-catalyzed system showed good catalytic activity. The desired products were affored in good to high yields (45%~96%).
- benzofuran,
- intramolecular Heck reaction,
- palladium nanoparticles
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