Citation: Zhang Kai, Li Jiarong, Wen Dusu, Liu Honglin, Wang Haiyou, Lamusi A. Study on the Synthesis and Insecticidal Activity of Spinosyn A Derivatives[J]. Chinese Journal of Organic Chemistry, ;2018, 38(12): 3363-3372. doi: 10.6023/cjoc201807001 shu

Study on the Synthesis and Insecticidal Activity of Spinosyn A Derivatives

Zhang Kai ^a ,
Li Jiarong ^a,, ,
Wen Dusu ^a ,
Liu Honglin ^b ,
Wang Haiyou ^b ,
Lamusi A ^b,,

a.
School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing 100081
b.
Institute of Grassland Research of Chinese Academy of Agricultural Sciences, Hohhot 010000

Corresponding author: Li Jiarong, jrli@bit.edu.cn Lamusi A,
Received Date: 1 July 2018
Revised Date: 2 August 2018
Available Online: 5 December 2018
Fund Project: the National Natural Science Foundation of China 41471198Project supported by the National Natural Science Foundation of China (No. 41471198)

Figures(2)

Spinosyns are a novel kind of biopesticide produced by Saccharopolyspora spinosa. Spinosyns have been widely applied in pest control because of their broad insecticidal spectrum, high insecticidal activity, low environmental impact, and low toxicity. To identify spinosyn compounds with improved insecticidal activity, a series of D-forosamine replacement derivatives of spinosyn A were synthesized. The insecticidal activities of the synthetic derivatives were evaluated against 3rd-instar larvae of Plutella xylostella. All derivatives exhibited good insecticidal activity to P. xylostella.
- natural product,
- spinosyn A,
- semi-synthetic derivative,
- insecticidal activity
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