Synthesis and Antitumor Evaluation of 2, 4-Substituted Quinazoline Derivatives Containing Benzimidazole
- Corresponding author: Ke Yu, ky@zzu.edu.cn Zhang Qiurong, zqr406@sina.com Liu Hongmin, liuhm@zzu.edu.cn
Citation:
Li Na, Xin Jingchao, Meng Yaqi, Li Erdong, Ma Qisheng, Bao Chongnan, Yang Peng, Song Panpan, Cui Fei, Zhao Peirong, Li Wen, Ke Yu, Zhang Qiurong, Liu Hongmin. Synthesis and Antitumor Evaluation of 2, 4-Substituted Quinazoline Derivatives Containing Benzimidazole[J]. Chinese Journal of Organic Chemistry,
;2018, 38(10): 2673-2679.
doi:
10.6023/cjoc201804016
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The cells were incubated with increasing concentrations of compounds 15e and 15k for 72 h. Then the number of viable cells was quantified spectrophotometrically by the MTT reagent
The hydrogen bonds were illustrated as black dashed lines (length unit in Å )