Citation: Xie Zhenda, Fu Manlin, Yin Biao, Zhu Qing. Research Progress in 1, 8-Naphthalimide-Based Fluorescent Probes for Two-Photon Imaging[J]. Chinese Journal of Organic Chemistry, ;2018, 38(6): 1364-1376. doi: 10.6023/cjoc201712031 shu

Research Progress in 1, 8-Naphthalimide-Based Fluorescent Probes for Two-Photon Imaging

Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310014

Corresponding author: Zhu Qing, zhuq@zjut.edu.cn
Received Date: 23 December 2017
Revised Date: 18 January 2018
Available Online: 6 June 2018
Fund Project: the National Natural Science Foundation of China 21272212the National Natural Science Foundation of China 21472172Project supported by the National Natural Science Foundation of China (Nos. 21472172, 21272212)

Figures(12)

Fluorescent imaging technology has received great attention owing to their advantageous features in high sensitivity, relatively simple operations and real-time living cells, tissue and in vivo imaging. Compared with one-photon confocal imaging, two-photon confocal imaging offers considerable advantages such as high resolution, deep-tissue depth, lower tissue auto-fluorescence and so on. As typical D-π-A two-photon dyes, 1, 8-naphthalimide dyes have wide application in two-photon imaging for enzyme, reactive carbon species, reactive oxygen species, reactive nitrogen species, biothiols and ions due to their advantages such as high photostability, large Stokes/anti-Stokes shifts. According to the mechanisms of intramolecular charge transfer, photoinduced electron transfer and fluorescence resonance energy transfer, etc., the application in two-photon imaging of 1, 8-naphthalimide dyes is summarized and emphasized.
- 1, 8-naphthalimide,
- fluorescent probe,
- D-π-A,
- fluorescent mechanism,
- two-photon imaging
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