Citation: Chen Bo, Liu Weishun, Zhang Jianfang, Liu Jiayi, Deng Guisheng. Synthesis of 3-Phosphonyl Pyrano[3, 2-c]pyrazol-7(1H)-one[J]. Chinese Journal of Organic Chemistry, ;2018, 38(4): 975-980. doi: 10.6023/cjoc201710030 shu

Synthesis of 3-Phosphonyl Pyrano[3, 2-c]pyrazol-7(1H)-one

a.
Ministry of Education of China), Hunan Normal University, Changsha 410081
b.
Key Laboratory of the Assembly and Application of Organic Functional Molecules, Hunan Normal University, Changsha 410081

Corresponding author: Deng Guisheng, gsdeng@hunnu.edu.cn
Received Date: 24 October 2017
Revised Date: 26 November 2017
Available Online: 5 April 2017
Fund Project: the Hunan Provincial Natural Science Foundation of China 2016JJ2080the National Natural Science Foundation of China 21372071Project supported by the National Natural Science Foundation of China (No. 21372071) and the Hunan Provincial Natural Science Foundation of China (No. 2016JJ2080)

Figures(4)

Base-mediated cyclization of 1-diazo-2, 4-dioxo-5-ynylphosphonate provided novel 3-phosphonyl pyrano[3, 2-c] pyrazol-7(1H)-one derivatives in 48%~99% yields. Mild conditions, simple manipulation and functional group diversity are the salient features of this methodology.
- synthesis,
- base,
- cyclization,
- pyrano[3, 2-c]pyrazol-7(1H)-one,
- phosphonate
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1.
沈阳化工大学材料科学与工程学院沈阳 110142