Citation: Zhu Xiaoyu, Zhao Yanan, Lan Liyan, Li Wenze. Enantioselective Organocatalytic Intramolecular Friedel-Crafts Alkylations of Pyrrole-Type Aryloxy-and Arylamino-tethered Enals: Access to a New Class of Pyrrole-Fused Heterocycles[J]. Chinese Journal of Organic Chemistry, ;2017, 37(12): 3163-3169. doi: 10.6023/cjoc201707003 shu

Enantioselective Organocatalytic Intramolecular Friedel-Crafts Alkylations of Pyrrole-Type Aryloxy-and Arylamino-tethered Enals: Access to a New Class of Pyrrole-Fused Heterocycles

College of Applied Chemistry, Shenyang University of Chemical Technology, Shenyang 110142

Corresponding author: Li Wenze, liwenze@syuct.edu.cn
Received Date: 4 July 2017
Revised Date: 23 August 2017
Available Online: 15 December 2017
Fund Project: Project supported by the National Natural Science Foundation of China (No. 21502118)the National Natural Science Foundation of China 21502118

Figures(2)

The catalytic asymmetric one-pot tandem intermolecular olefin cross-metathesis/intramolecular Friedel-Crafts alkylation with aryloxy-and arylamino-tethered enals as building blocks was developed, which offers a direct and convenient access to a novel type of pyrrole-fused heterocyclic compounds in good yields with synthetically useful enantioselectivities.
- pyrrole-fused heterocycles,
- olefin cross-metathesis,
- Friedel-Crafts alkylation,
- asymmetric synthesis,
- one pot
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