Citation: Li Qilin, Zhang Hongbin. Research Progress on the Synthesis of Morphine Alkaloids[J]. Chinese Journal of Organic Chemistry, ;2017, 37(7): 1629-1652. doi: 10.6023/cjoc201702048 shu

Research Progress on the Synthesis of Morphine Alkaloids

Li Qilin ^a,b ,
Zhang Hongbin ^b,,

a.
Earthquake Administration of Yunnan Province, Kunming 650224
b.
Key Laboratory of Medicinal Chemistry for Natural Resource Ministry of Education, Yunnan University, Kunming 650091

Corresponding author: Zhang Hongbin, zhanghb@ynu.edu.cn
Received Date: 28 January 2017
Revised Date: 22 March 2017
Available Online: 13 July 2017
Fund Project: the Program for Changjiang Scholars and Innovative Research Team in University IRT13095the National Natural Science Foundation of China 21332007Project supported by the Program for Changjiang Scholars and Innovative Research Team in University (No. IRT13095), and the National Natural Science Foundation of China (Nos. 20925205, 21332007)the National Natural Science Foundation of China 20925205

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The morphine alkaloids constitute a class of structurally related natural products isolated from opium poppy, Papaver somniferum. The synthesis of morphine and its derivatives has attracted the attention of many generations of synthetic chemists due to their highly challenging molecular architecture and biological activities. Progresses toward the synthesis of the morphine alkaloids are reviewed in terms of chronological order.
- morphine,
- morphine alkaloids,
- synthesis
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