Citation: Dai Yi, Zhong Fei. Advances in the Study of Structural Modification and Biological Activities of Oridonin[J]. Chinese Journal of Organic Chemistry, ;2017, 37(7): 1701-1713. doi: 10.6023/cjoc201702011 shu

Advances in the Study of Structural Modification and Biological Activities of Oridonin

Dai Yi ^a,c,, ,
Zhong Fei ^b

a.
Pharmacology College, Anhui Xinhua University, Hefei 230088
b.
Department of Oncology, First Affiliated Hospital, Anhui Medical University, Hefei 230022
c.
Department of Chemistry, University of Science and Technology of China, Hefei 230026

Corresponding author: Dai Yi, daiyi@mail.ustc.edu.cn
Received Date: 9 February 2017
Revised Date: 7 March 2017
Available Online: 17 July 2017
Fund Project: Project supported by the Key National Natural Science Foundation of Department of Education of Anhui Province (No. KJ2016A301)the Key National Natural Science Foundation of Department of Education of Anhui Province KJ2016A301

Figures(13)

Oridonin, an ent-kaurane diterpenoid, is found in the Chinese herb Rabdosia rubescens and some related species, and has various biological activities such as anti-tumor, anti-microbial, anti-inflammatory, and so on.This review provides an overview of the multifunctional effects of the structural modification of oridonin since 2000, suggesting that it may be effective choice for improving pharmacological activities.
- oridonin,
- structural modification,
- anti-cancer activity,
- anti-mycobacterial activity
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