Citation: Zhao Yuying, Wang Erbing, Wang Yingli. Iodine-Promoted Three-Component Reaction of β-Keto Esters, Chalcones and Ammonium Acetate for the Synthesis of Poly-substituted Pyridines[J]. Chinese Journal of Organic Chemistry, ;2017, 37(4): 866-872. doi: 10.6023/cjoc201701006 shu

Iodine-Promoted Three-Component Reaction of β-Keto Esters, Chalcones and Ammonium Acetate for the Synthesis of Poly-substituted Pyridines

a.
Institute of Chemical and Biological Technology, Taiyuan University of Science and Technology, Taiyuan 030021
b.
Department of Traditional Chinese Pharmacology, Shanxi University of Traditional Chinese Medicine, Taiyuan 030024

Corresponding author: Zhao Yuying, zhaoyuyingtyust@163.com
Received Date: 5 January 2017
Revised Date: 5 March 2017

Fund Project: the Science and Technology Key Project of Shanxi Province 20130313015-2

Figures(3)

A three-component reaction for the synthesis of poly-substituted pyridines from β-keto esters, chalcones and ammonium acetate promoted by iodine has been reported. Advantages of the present method include ready availability of starting materials, broad scope of substrates, and convenience of operation.
- molecular iodine,
- muti-component reaction,
- pyridine
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