Citation: Yu Zhengwei, Li Linyi, Shen Zengming. Cu-Catalyzed Cyanation of Aryl Iodides with Acetonitrile as Cyano Source[J]. Chinese Journal of Organic Chemistry, ;2017, 37(5): 1273-1277. doi: 10.6023/cjoc201612015 shu

Cu-Catalyzed Cyanation of Aryl Iodides with Acetonitrile as Cyano Source

School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai 200240

Corresponding author: Shen Zengming, shenzengming@sjtu.edu.cn
Received Date: 6 December 2016
Revised Date: 5 January 2017

Fund Project: Project supported by the National Natural Sciences Foundation of China 21272001and the Shanghai Education Committee 13ZZ014Project supported by the National Natural Sciences Foundation of China 21672144

Figures(2)

A Cu-catalyzed protocol for the cyanation of aryl iodides by using acetonitrile as the "CN" source has been developed, in which the Cu(cat.)/2, 2, 6, 6-tetramethyl-1-piperidinyloxy (TEMPO)/Si system shows good reactivity and generality. Both electron-rich and electron-deficient functional groups can be tolerated in this system.
- Cu catalyst,
- cyanation,
- acetonitrile,
- aryl iodide,
- 2, 2, 6, 6-tetramethyl-1-piperidinyloxy (TEMPO)
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