Citation: Liu Ruihuan, Wang Xuli, Cheng Fei, Li Fushuang, Xu Kangping, Tan Guishan. Ce (SO₄)₂·4H₂O Mediated Synthesis of Flavones and 2-Phenyl-4-quinolones[J]. Chinese Journal of Organic Chemistry, ;2016, 36(11): 2677-2682. doi: 10.6023/cjoc201603036 shu

Ce (SO₄)₂·4H₂O Mediated Synthesis of Flavones and 2-Phenyl-4-quinolones

Liu Ruihuan ^a ,
Wang Xuli ^a ,
Cheng Fei ^a ,
Li Fushuang ^a ,
Xu Kangping ^a,*,, ,
Tan Guishan ^a,b

a.
Department of Pharmacy, Central South University, Changsha 410013
b.
Xiangya Hospital, Central South University, Changsha 410013

Corresponding author: Xu Kangping, xukp395@csu.edu.cn
Received Date: 22 March 2016
Revised Date: 20 June 2016

Fund Project: the National Natural Science Foundation of China 31370370the Social Development of Science and Technology Project of Hainan Province SF201419the Science and Technology Planning Project of Hunan Pprovince 2013SK5077

A simple and powerful procedure for the synthesis of flavones and quinolones was developed by using Ce (SO₄)₂·4H₂O as oxidant, readily available 2'-hydroxychalcones and 2'-aminochalcones as raw materials, and dimethyl sulfoxide (DMSO) as solvent at 110℃. The new procedure is characterized with raw material easy to get, low manufacturing cost, mild reaction condi-tions and high yields.
- Ce (SO₄)₂·4H₂O,
- 2'-hydrochalcone,
- 2'-aminochalcone,
- flavone,
- quinolone
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Ce (SO₄)₂·4H₂O Mediated Synthesis of Flavones and 2-Phenyl-4-quinolones