Citation: Geng Qian, Li Zining, Lü Zhe, Liang Guangxin. Progress in Total Syntheses of Leuconolam- Leuconoxine-Mersicarpine Alkaloids[J]. Chinese Journal of Organic Chemistry, ;2016, 36(7): 1447-1464. doi: 10.6023/cjoc201603030 shu

Progress in Total Syntheses of Leuconolam- Leuconoxine-Mersicarpine Alkaloids

Geng Qian ^a ,
Li Zining ^a ,
Lü Zhe ^a ,
Liang Guangxin ^a,b,*,,

a.
State Key Laboratory of Elemento-organic Chemistry, Nankai University, Tianjin 300071
b.
Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin 300071

Corresponding author: Liang Guangxin, lianggx@nankai.edu.cn
Received Date: 17 March 2016
Revised Date: 27 April 2016

Fund Project: the National Natural Science Foundation of China Nos. 21372127, 21572104

Figures(25)

Leuconolam-leuconoxine-mersicarpine monoterpene indole alkaloids are mainly isolated from Apocynaceae Kopsia species of plant. Though sharing the same biogenetic origin, they are a family of natural products showing incredible structural complexity and diversity. Moreover, many of them exhibit excellent bioactivities, for example, anti-inflammatory, anti-tumor activities. The progress in the total synthesis of this remarkable family of alkaloids is reviewed.
- leuconolam,
- leuconoxine,
- mersicarpine,
- monoterpene indole alkaloid,
- total synthesis
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