Citation: Wang Gang, Guo Yan, Lü Ying, Wang Xicun, Quan Zhengjun. Synthesis of 1,2-Di(pyrimidin-2-yl)disulfides from the Oxidative Coupling and Aromatization of 3,4-Dihydropyrimidin-2-thiones by Using 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone as Oxidant[J]. Chinese Journal of Organic Chemistry, ;2016, 36(6): 1375-1381. doi: 10.6023/cjoc201512038 shu

Synthesis of 1,2-Di(pyrimidin-2-yl)disulfides from the Oxidative Coupling and Aromatization of 3,4-Dihydropyrimidin-2-thiones by Using 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone as Oxidant

Wang Gang ^a ,
Guo Yan ^a ,
Lü Ying ^a,b ,
Wang Xicun ^a,*,, ,
Quan Zhengjun ^a,*,,

a.
College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070
b.
Lanzhou No. 46 Middle School, Lanzhou 730030

Corresponding author: Wang Xicun, wangxicun@nnwu.edu.cn Quan Zhengjun, quanzhengjun@hotmail.com
Received Date: 25 December 2015
Revised Date: 21 January 2016

Fund Project: Project supported by the National Natural Science Foundation of China Nos. 21362032, 21362031

Figures(4)

The oxidative coupling and aromatization of 3,4-dihydropyrimidin-2-thiones to produce 1,2-di(pyrimidin-2-yl)- disulfides by using 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) as oxidant at room temperature under an air atmosphere are reported. Compared with the reported procedures, this method has obvious advantages at mild reaction conditions including lower reaction temperature and shorter reaction time with higher yields of products.
- 3,4-dihydropyrimidin-2-thiones,
- 1,2-di(pyrimidin-2-yl) disulfides,
- DDQ,
- oxidative coupling
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