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Citation: Chen Xiaowei, Chong Siying, Du Ganggang, Huang Danfeng, Wang Kehu, Su Yingpeng, Hu Yulai. Diacetoxyiodobenzene Promoted Chlorination of Silyl Enol Ether of Aryl Ketones[J]. Chinese Journal of Organic Chemistry, ;2016, 36(5): 1028-1033. doi: 10.6023/cjoc201511041 shu

Diacetoxyiodobenzene Promoted Chlorination of Silyl Enol Ether of Aryl Ketones

1.
College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070

Corresponding author: Su Yingpeng, suyp51@nwnu.edu.cn Hu Yulai, huyl@nwnu.edu.cn
Received Date: 19 November 2015
Revised Date: 30 December 2015

Fund Project: Project supported by the National Natural Science Foundation of China Nos.21362033,21502154

Figures(2)

A series of α-chloroketones were obtained from silyl enol ethers of aryl ketones using trimethylchlorosilane as chlorine source and diacetoxyiodobenzene as promoter. The reaction occurs under mild condition yielding the product in moderate to good yields, and has the potential possibility for the synthesis of α-bromoketone by using trimethyl bromosilane as bromine source.
- α-chlorination,
- diacetoxyiodobenzene,
- silyl enol ether,
- aryl ketone,
- α-bromoaryl ketone
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