Citation: Yang Taiqun, Dai Shan, Qin Cuifang, Huang Kehan, Chen Yuting, Pan Haifeng, Zhang Sanjun, Zhang Kun, Xu Jianhua. Selective Detection of Homocysteine by Using Poly Methyl Vinyl Ether-alt-Maleic Silver Clusters[J]. Chinese Journal of Organic Chemistry, ;2016, 36(4): 867-871. doi: 10.6023/cjoc201511023 shu

Selective Detection of Homocysteine by Using Poly Methyl Vinyl Ether-alt-Maleic Silver Clusters

Yang Taiqun ^a,b ,
Dai Shan ^a ,
Qin Cuifang ^a ,
Huang Kehan ^a ,
Chen Yuting ^a ,
Pan Haifeng ^a ,
Zhang Sanjun ^a,c,, ,
Zhang Kun ^b ,
Xu Jianhua ^a,c

a.
a. State Key Laboratory of Precision Spectroscopy, East China. Normal University, Shanghai 200062;
b.
b. Shanghai Key Laboratory of Green Chemistry and Chemical Processes, Department of Chemistry East China. Normal University, Shanghai 200062;
c.
c. Collaborative Innovation Center of Extreme Optics, Shanxi University, Taiyuan 030006

Corresponding author: Zhang Sanjun,
Received Date: 13 November 2015
Available Online: 3 December 2015
Fund Project: 上海市自然科学基金(No.15ZR1410100) (No.15ZR1410100)国家自然科学基金(No.61178085)资助项目. (No.61178085)

We report selective detection of homocysteine (Hcy) through luminescent poly methyl vinyl ether-alt-maleic acid (PMVEM) silver nanoclusters (Ag NCs), which were synthesized using PMVEM as scaffold. The as-developed PMVEM-Ag NCs have two emission peaks at 460 and 540 nm. After Hcy was added, the thiol moiety of Hcy can efficiently coordinate on Ag NCs, resulting in luminescence quenching of the 460 and 540 nm peaks. However, the ratio of these two emission peak was linearly correlated with the Hcy concentration from 5 to 100 μmol/L. The detection limits was 1 μmol/L. The detection of Hcy used the ratio of the two emission peaks, which permit selective detection of Hcy and quantitive determination of Hcy levels.
- homocysteine,
- poly methyl vinyl ether-alt-maleic acid,
- fluorescent sensor,
- silver nanoclusters
1. [1]
  [1] Wood, Z. A.; Schroder, E.; Robin Harris, J.; Poole, L. B. TRENDS Biochem. Sci. 2003, 28.
2. [2]
  [2] Zhou, Y.; Yoon, J. Chem. Soc. Rev. 2012, 41, 52.
3. [3]
  [3] Zhou, J. D.; Cao, F.; Zhang, X. L.; Yang, Y.; Ying, H. J.; Wei, P. Chin. J. Org. Chem. 2009, 29, 1272 (in Chinese). (周佳栋, 曹飞, 张小龙, 杨颖, 应汉杰, 韦萍, 有机化学, 2009, 29, 1272.)
4. [4]
  [4] Yu, C. M.; Zeng, F.; Luo, M.; Wu, S. Z. Nanotechnology 2012, 23.
5. [5]
  [5] Sukul, P. K.; Santra, D. C.; Singh, P. K.; Maji, S. K.; Malik, S. New J. Chem. 2015, 39, 5084.
6. [6]
  [6] Liu, T.; Huo, F. J.; Yin, C. X.; Li, J. F.; Niu, L. X. RSC Adv. 2015, 5, 28713.
7. [7]
  [7] Stich, M. I.; Fischer, L. H.; Wolfbeis, O. S. Chem. Soc. Rev. 2010, 39, 3102.
8. [8]
  [8] Wang, J.; Moore, J.; Laulhe, S.; Nantz, M.; Achilefu, S.; Kang, K. A. Nanotechnology 2012, 23, 095501.
9. [9]
  [9] Jin, R. Nanoscale 2010, 2, 343.
10. [10]
  [10] Diez, I.; Ras, R. H. Nanoscale 2011, 3, 1963.
11. [11]
  [11] Zheng, J.; Zhang, C.; Dickson, R. M. Phys. Rev. Lett. 2004, 93.
12. [12]
  [12] Yu, J.; Patel, S. A.; Dickson, R. M. Angew. Chem., Int. Ed. 2007, 46, 2028.
13. [13]
  [13] Choi, S.; Dickson, R. M.; Yu, J. Chem. Soc. Rev. 2012, 41, 1867.
14. [14]
  [14] Shang, L.; Dong, S. Chem. Commun. 2008, 1088.
15. [15]
  [15] Chen, Y.; Yang, T.; Pan, H.; Yuan, Y.; Chen, L.; Liu, M.; Zhang, K.; Zhang, S.; Wu, P.; Xu, J. J. Am. Chem. Soc. 2014, 136, 1686.
16. [16]
  [16] Yuping, B.; Chang, Z.; Vu, D. M.; Temirov, J. P.; Dyer, R. B.; Martinez, J. S. J. Phys. Chem. C 2007, 111, 12194.
17. [17]
  [17] Wu, Z.; Jin, R. Nano Lett. 2010, 10, 2568.
1. [1]
  Jinlong YAN , Weina WU , Yuan WANG . A simple Schiff base probe for the fluorescent turn-on detection of hypochlorite and its biological imaging application. Chinese Journal of Inorganic Chemistry, 2024, 40(9): 1653-1660. doi: 10.11862/CJIC.20240154
2. [2]
  Jun LUO , Baoshu LIU , Yunchang ZHANG , Bingkai WANG , Beibei GUO , Lan SHE , Tianheng CHEN . Europium(Ⅲ) metal-organic framework as a fluorescent probe for selectively and sensitively sensing Pb²⁺ in aqueous solution. Chinese Journal of Inorganic Chemistry, 2024, 40(12): 2438-2444. doi: 10.11862/CJIC.20240240
3. [3]
  Yu SU , Xinlian FAN , Yao YIN , Lin WANG . From synthesis to application: Development and prospects of InP quantum dots. Chinese Journal of Inorganic Chemistry, 2024, 40(11): 2105-2123. doi: 10.11862/CJIC.20240126
4. [4]
  Meirong HAN , Xiaoyang WEI , Sisi FENG , Yuting BAI . A zinc-based metal-organic framework for fluorescence detection of trace Cu²⁺. Chinese Journal of Inorganic Chemistry, 2024, 40(8): 1603-1614. doi: 10.11862/CJIC.20240150
5. [5]
  Yuan ZHU , Xiaoda ZHANG , Shasha WANG , Peng WEI , Tao YI . Conditionally restricted fluorescent probe for Fe³⁺ and Cu²⁺ based on the naphthalimide structure. Chinese Journal of Inorganic Chemistry, 2025, 41(1): 183-192. doi: 10.11862/CJIC.20240232
6. [6]
  Shuwen SUN , Gaofeng WANG . Design and synthesis of a Zn(Ⅱ)-based coordination polymer as a fluorescent probe for trace monitoring 2, 4, 6-trinitrophenol. Chinese Journal of Inorganic Chemistry, 2025, 41(4): 753-760. doi: 10.11862/CJIC.20240399
7. [7]
  Jiakun BAI , Ting XU , Lu ZHANG , Jiang PENG , Yuqiang LI , Junhui JIA . A red-emitting fluorescent probe with a large Stokes shift for selective detection of hypochlorous acid. Chinese Journal of Inorganic Chemistry, 2024, 40(6): 1095-1104. doi: 10.11862/CJIC.20240002
8. [8]
  Chengqian Mao , Yanghan Chen , Haotong Bai , Junru Huang , Junpeng Zhuang . Photodimerization of Styrylpyridinium Salt and Its Application in Silk Screen Printing. University Chemistry, 2024, 39(5): 354-362. doi: 10.3866/PKU.DXHX202312014
9. [9]
  Zongfei YANG , Xiaosen ZHAO , Jing LI , Wenchang ZHUANG . Research advances in heteropolyoxoniobates. Chinese Journal of Inorganic Chemistry, 2024, 40(3): 465-480. doi: 10.11862/CJIC.20230306
10. [10]
  Yi DING , Peiyu LIAO , Jianhua JIA , Mingliang TONG . Structure and photoluminescence modulation of silver(Ⅰ)-tetra(pyridin-4-yl)ethene metal-organic frameworks by substituted benzoates. Chinese Journal of Inorganic Chemistry, 2025, 41(1): 141-148. doi: 10.11862/CJIC.20240393
11. [11]
  Qin Hou , Jiayi Hou , Aiju Shi , Xingliang Xu , Yuanhong Zhang , Yijing Li , Juying Hou , Yanfang Wang . Preparation of Cuprous Iodide Coordination Polymer and Fluorescent Detection of Nitrite: A Comprehensive Chemical Design Experiment. University Chemistry, 2024, 39(8): 221-229. doi: 10.3866/PKU.DXHX202312056
12. [12]
  Yuhao SUN , Qingzhe DONG , Lei ZHAO , Xiaodan JIANG , Hailing GUO , Xianglong MENG , Yongmei GUO . Synthesis and antibacterial properties of silver-loaded sod-based zeolite. Chinese Journal of Inorganic Chemistry, 2024, 40(4): 761-770. doi: 10.11862/CJIC.20230169
13. [13]
  Laiying Zhang , Yaxian Zhu . Exploring the Silver Family. University Chemistry, 2024, 39(9): 1-4. doi: 10.12461/PKU.DXHX202409015
14. [14]
  Zhiwen HUANG , Qi LIU , Jianping LANG . W/Cu/S cluster-based supramolecular macrocycles and their third-order nonlinear optical responses. Chinese Journal of Inorganic Chemistry, 2025, 41(1): 79-87. doi: 10.11862/CJIC.20240184
15. [15]
  Yuan GAO , Yiming LIU , Chunhui WANG , Zhe HAN , Chaoyue FAN , Jie QIU . A hexanuclear cerium oxo cluster stabilized by furoate: Synthesis, structure, and remarkable ability to scavenge hydroxyl radicals. Chinese Journal of Inorganic Chemistry, 2025, 41(3): 491-498. doi: 10.11862/CJIC.20240271
16. [16]
  Xiao SANG , Qi LIU , Jianping LANG . Synthesis, structure, and fluorescence properties of Zn(Ⅱ) coordination polymers containing tetra-alkenylpyridine ligands. Chinese Journal of Inorganic Chemistry, 2024, 40(11): 2124-2132. doi: 10.11862/CJIC.20240158
17. [17]
  Zhaoyang WANG , Chun YANG , Yaoyao Song , Na HAN , Xiaomeng LIU , Qinglun WANG . Lanthanide(Ⅲ) complexes derived from 4′-(2-pyridyl)-2, 2′∶6′, 2″-terpyridine: Crystal structures, fluorescent and magnetic properties. Chinese Journal of Inorganic Chemistry, 2024, 40(8): 1442-1451. doi: 10.11862/CJIC.20240114
18. [18]
  Jinghan ZHANG , Guanying CHEN . Progress in the application of rare-earth-doped upconversion nanoprobes in biological detection. Chinese Journal of Inorganic Chemistry, 2024, 40(12): 2335-2355. doi: 10.11862/CJIC.20240249
19. [19]
  Feiyang Liu , Liuhong Song , Miaoyu Fu , Zhi Zheng , Gang Xie , Junlong Zhao . Tryptophan’s Employment Journey. University Chemistry, 2024, 39(9): 16-21. doi: 10.12461/PKU.DXHX202404037
20. [20]
  Liyang ZHANG , Dongdong YANG , Ning LI , Yuanyu YANG , Qi MA . Crystal structures, luminescent properties and Hirshfeld surface analyses of three cadmium(Ⅱ) complexes based on 2-(3-(pyridin-2-yl)-1H-pyrazol-1-yl)benzoate. Chinese Journal of Inorganic Chemistry, 2024, 40(10): 1943-1952. doi: 10.11862/CJIC.20240079

Get Citation

PDF

XML

Metrics

PDF Downloads(0)
Abstract views(832)
HTML views(96)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142