Citation: Mostafa M H Khalil, Eglal R Souaya, Eman H Ismail, Eman Rabie. Ternary Transition Metal Complexes of Nitrilotriacetic Acid and Valine or Leucine:Synthesis and Biological Applications[J]. Chinese Journal of Inorganic Chemistry, ;2013, 29(9): 1969-1978. doi: 10.3969/j.issn.1001-4861.2013.00.319
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Ternary complexes of Ni(Ⅱ), Cu(Ⅱ), and Zn(Ⅱ) with nitrilotriacetic acid HNTA2- as a primary ligand and valine or leucine as a secondary ligand were synthesized in slightly acidic medium. The new complexes were characterized by elemental analysis, FTIR, UV-Vis spectroscopy, thermal analysis, magnetic measurements and mass spectroscopy. The results indicate that the ternary complexes are isolated in M:HNTA:valine(or leucine) ratio of 1:1:1, and the molecular structures are suggested to be[M(HNTA)(valine)(H2O)2]·1.5H2O and[M(HNTA) (leucine)(H2O)2]·1.5H2O, where M=Ni(Ⅱ) or Cu(Ⅱ) and H2[Zn(NTA)(valine)(H2O)] H2O. The suggested geometry of our ternary metal complexes is an octahedral symmetry. The antimicrobial activities of prepared complexes against Escherichia coli, Staphylococcus aureus, Candida albicans and Aspergillus flavus (isolates from Microanalytical Center, Faculty of Science, Cairo University) were also investigated. The complexes were tested in vitro to assess growth inhibitory activity against the bacterial and fungal species with standard antibacterial and antifungal agents according to the recommended known method.
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-
[1]
[1] Charlot M F, Kahn O, Jeannin S, et al. Inorg. Chem., 1980, 19:1411-1416
-
[2]
[2] Sigel H, Operschall B P, Massoud S S, et al. Dalton Trans., 2006,46:5521-5529
-
[3]
[3] Czakis-Sulikowska D, Czylkowska A, Radwanska D, et al. J. Therm. Anal. Cal., 2007,90:557-564.
-
[4]
[4] Bocarsly J R, Barton J K. Inorg. Chem., 1992,31:2827-2832
-
[5]
[5] Farver O, Pecht I. Coord. Chem. Rev., 1989,95:17-23
-
[6]
[6] Crowe J, Dobeli H, Gentz R, et al. Methods Mol. Bio., 1994, 31:371-387
-
[7]
[7] Nieba-Axmann S E, Persson A, Hamalainen M, et al. Anal. Biochem., 1997,252:217-222
-
[8]
[8] Maloriery K M, Shnek D R, Sasaki D Y, et al. Chem. Biol., 1996,3:185-192
-
[9]
[9] Bumba L, Tichy M, Dobakova M, et al. J. Struct. Bio., 2005, 152:28-35
-
[10]
[10] Hu Q H, Li X F, Du G C, et al. J. Chem. Engin., 2008,143: 111-116
-
[11]
[11] Ben Hander G M. Res. J. Chem. Sci., 2012,2(3):12-20
-
[12]
[12] Anderson R L, Bishop W E, Campbell R L. Crit. Re. Toxicol.,1985,15(1):1-102
-
[13]
[13] IARC: Nitrilotriacetic Acid and Its Salts. In: "IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Humans", IARC, Lyons. 1990,48:181-214
-
[14]
[14] Evangelou M W H, Ebel M, Schaeffer A. Chemosphere, 2007,68(6):989-1003
-
[15]
[15] Kaur G, Hasan S K, Srivastava R C. Archives of toxicology, 1980,45:203-206
-
[16]
[16] Pollack S, Ruocco S. in vivo. Blood., 1981,57(6):1117-1118
-
[17]
[17] Mendola M E, Paul T, Strathmann T J, et al. Polyhedron, 2009,28:269-78
-
[18]
[18] Kumita H, Jitsukawa K, Masuda H, et al. Inorg. Chim. Acta, 1998,283:160-166
-
[19]
[19] Anderegg G, Komplexone X L, Helv. Chim. Acta, 1967,50: 2333-40
-
[20]
[20] Hopgood D, Augelici R J. J. Am. Chem. Soc., 1968,90: 2508-13
-
[21]
[21] Chohan H Z, Arif M, Akhtar M A, et al. Bioinorg. Chem. Appl., 2006,1:83131 DOI: 10.1155/BCA/2006/83131
-
[22]
[22] Sakyan I, Logoglu E, Arslan S, et al. Biometals, 2004,17(2): 115-120
-
[23]
[23] Chohan H Z, Arif M, Sarfraz M. Appl. Organomet. Chem., 2007,21(4):294-302
-
[24]
[24] Ramakrishna R, Ashis K, Patra P, et al. Polyhedron, 2008, 27:1343-1352
-
[25]
[25] Jian fang D, Lianzhi L, Guihua L, et al. J. Mol. Struc., 2011, 986:57-63
-
[26]
[26] Jian L, Tingting L, Sulan C, et al. J. Inorg. Biochem., 2006, 100:1888-1896
-
[27]
[27] Khalil M, Hamed E, Abdel Azim S et al. J. Therm. Anal. Calorim., 2010,101:129-135
-
[28]
[28] Dawson R M C. Data for Biochemical Research, Oxford: Clarendon Press, 1959.
-
[29]
[29] Santi E, Torre M H, Kremer E, et al. J. Vib. Spectrosc., 1993,5:285-93
-
[30]
[30] Ismail E H, Souaya E R, Amr A M. J. Appl. Poly. Sci., 2012,124(3):1976-1980
-
[31]
[31] Souaya E R, Ismail E H, Mohamed A A, et al. J. Therm. Anal. Calorim., 2009,95:553-558
-
[32]
[32] Gabbott P. Principles and Applications of Thermal Analysis. 1st ed. UK: Blackwell Publishing Ltd., 2008.
-
[33]
[33] Shengli J, Mian J, Sanping C, et al. J. Therm. Anal. Calorim., 2001,66:423-429.
-
[34]
[34] Chartone-Souza E, Loyola T L, Rodriguez M B, et al. J. Inorg. Biochem., 2005,99:1001-1008
-
[35]
[35] Gordon A S, Howell L D, Harwood V C. J. Microbiol., 1994, 40:408-411
-
[36]
[36] Jawetz E, Melnick J L, Adelberg E A. Review of Medical Microbiology, 16th Ed., Los Anglos, CA: Lang Medical Publications1979.
-
[37]
[37] Hughes W H, Stewart H C. Concise Antibiotic Treatment Butter Worth, London 1970.
-
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