Citation: CHEN Fan, WANG Zhong-Yue, ZHANG Yan-Yan, YU Ke-Han, WENG Li-Xing, WEI Wei. Synthesis of Poly(acrylic acid)-Functionalized La1-xEuxF3 Nanocrystals with High Photoluminescence for Cellular Imaging[J]. Acta Physico-Chimica Sinica, ;2017, 33(7): 1446-1452. doi: 10.3866/PKU.WHXB201704102
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Monodisperse La1-xEuxF3 nanoparticles (NPs) were functionalized by poly(acrylic acid) (PAA) via a one-pot modified hydrothermal method. The morphology, crystal structure, surface groups, and luminescence properties of the as-produced La1-xEuxF3@PAA NPs were characterized by transmission electron microscopy (TEM), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), and photoluminescence (PL) spectroscopy. The produced nanoparticles were (7±3) nm in size, water soluble, and buffer stable, with good photostability and biocompatibility. In vitro imaging revealed the low cytotoxicity of the as-synthesized NPs incubated with HeLa cancer cells. Thus, the colloidal La1-xEuxF3@PAA NPs exhibit great potential for use as optical imaging probes in biological applications.
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