Citation: QIAO Rui-Rui, ZENG Jian-Feng, JIA Qiao-Juan, DU Jun, SHEN Lin, GAO Ming-Yuan. Magnetic Iron Oxide Nanoparticle——an Important Cornerstone of MR Molecular Imaging of Tumors[J]. Acta Physico-Chimica Sinica, ;2012, 28(05): 993-1011. doi: 10.3866/PKU.WHXB201203023 shu

Magnetic Iron Oxide Nanoparticle——an Important Cornerstone of MR Molecular Imaging of Tumors

1.
1. Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China;
2. Laboratory of Microbial and Biochemical Pharmacy, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, P. R. China;
3. Beijing Institute for Cancer Research, Peking University School of Oncology, Beijing 100036, P. R. China

Received Date: 15 January 2012
Available Online: 2 March 2012
Fund Project: 国家重点基础研究发展计划(973) (2011CB935800) (973) (2011CB935800)国家自然科学基金(81090271, 21003135, 20820102035)资助项目 (81090271, 21003135, 20820102035)

This review summaries the syntheses and applications of magnetic iron oxide nanocrystals that have been published worldwide. In particular, it discusses the future applications of magnetic iron oxide nanoparticles in molecular imaging of tumors.
- Magnetic nanoparticle,
- Tumor,
- Magnetic resonance,
- Molecular imaging,
- Multi-modality
1. [1]
  (1) Ferlay, J.; Bray, F.; Forman, D; Mathers, C. D; Parkin, D. Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 10. Lyon, France: International Agency for Research on Cancer. Available at: http://globocan.iarc.fr. 2010. Last accessed 8/17/2010. GLOBOCAN 2008.
2. [2]
  (2) Weissleder, R. Science 2006, 312, 1168.
3. [3]
  (3) Weissleder, R.; Pittet, M. J. Nature 2008, 452, 580.
4. [4]
  (4) Wagner, V.; Dullaart, A.; Bock, A. K.; Zweck, A. Nat. Biotechnol. 2006, 24, 1211.
5. [5]
  (5) Corot, C.; Robert, P.; Idee, J. M.; Port, M. Adv. Drug Deliv. Rev. 2006, 58, 1471.
6. [6]
  (6) Briley-Saebo, K.; Bjornerud, A.; Grant, D.; Ahlstrom, H.; Berg, T.; Kindberg, G. M. Cell Tissue Res. 2004, 316, 315.
7. [7]
  (7) Qiao, R. R.; Yang, C. H.; Gao, M. Y. J. Mater. Chem. 2009, 19, 6274.
8. [8]
  (8) Harisinghani, M. G.; Barentsz, J.; Hahn, P. F.; Deserno, W. M.; Tabatabaei, S.; van de Kaa, C. H.; de la Rosette, J.; Weissleder, R. N. Engl. J. Med. 2003, 348, 2491.
9. [9]
  (9) Huh, Y. M.; Jun, Y. W.; Song, H. T.; Kim, S.; Choi, J. S.; Lee, J. H.; Yoon, S.; Kim, K. S.; Shin, J. S.; Suh, J. S.; Cheon, J. J. Am. Chem. Soc. 2005, 127, 12387.
10. [10]
  (10) Hu, F. Q.; Wei, L.; Zhou, Z.; Ran, Y. L.; Li, Z.; Gao, M. Y. Adv. Mater. 2006, 18, 2553.
11. [11]
  (11) Murakami, H.; Nakashima, N. J. Nanosci. Nanotechnol. 2006, 6, 16.
12. [12]
  (12) Mikawa, M.; Kato, H.; Okumura, M.; Narazaki, M.; Kanazawa, Y.; Miwa, N.; Shinohara, H. Bioconjugate Chem. 2001, 12, 510.
13. [13]
  (13) Jain, P. K.; Lee, K. S.; El-Sayed, I. H.; El-Sayed, M. A. J. Phys. Chem. B 2006, 110, 7238.
14. [14]
  (14) Gao, X. H.; Cui, Y. Y.; Levenson, R. M.; Chung, L. W. K.; Nie, S. M. Nat. Biotechnol. 2004, 22, 969.
15. [15]
  (15) Jordan, A.; Scholz, R.; Wust, P.; Fähling, H.; Krause, J.; Wlodarczyk, W.; Sander, B.; Vogl, T.; Felix, R. Int. J. Hyperthermia 1997, 13(6), 587.
16. [16]
  (16) Veiseh, O.; Gunn, J. W.; Zhang, M. Q. Adv. Drug Deliv. Rev. 2010, 62, 284.
17. [17]
  (17) Yang, W. Gao, M. Y.; Bai, Y. Nanomaterials and Biotechnologies, 1st ed.; Chemical Industry Press; Beijing, 2005; pp 53-177 [杨文胜, 高明远, 白玉白. 纳米材料与生物技术, 第一版; 化学工业出版社: 北京, 2005; 53-177.]
18. [18]
  (18) Degen, C. L.; Poggio, M.; Mamin, H. J.; Rettner, C. T.; Rugar, D. Proc. Natl. Acad. Sci. U. S. A. 2009, 106, 1313.
19. [19]
  (19) Fischer, U.; Brinck, U. Practical MR mammography. Stuttgart: Georg Thieme Verlag, 2003.
20. [20]
  (20) Qiao, R. R.; Jia, Q. J.; Zeng, J. F.; Gao, M. Y. Acta Biophys. Sinca 2011, 27, 272. [乔瑞瑞, 贾巧娟, 曾剑峰, 高明远. 生物物理学报, 2011, 27, 272.]
21. [21]
  (21) De Leon-Rodriguez, L. M.; Lubag, A. J. M.; Malloy, C. R.; Martinez, G. V.; Gillies, R. J.; Sherry, A. D. Accounts Chem. Res. 2009, 42, 948.
22. [22]
  (22) Rad, A. M.; Arbab, A. S.; Iskander, A. S. M.; Jiang, Q.; Soltanian-Zadeh, H. J. Magn. Reson. Imaging 2007, 26, 366.
23. [23]
  (23) Tanaka, K.; Narita, A.; Kitamura, N.; Uchiyama, W.; Morita, M.; Inubushi, T.; Chujo, Y. Langmuir 2010, 26, 11759.
24. [24]
  (24) Heesakkers, R. A. M.; Jager, G. J.; Hovels, A. M.; de Hoop, B.; van den Bosch, H. C. M.; Raat, F.; Witjes, J. A.; Mulders, P. F. A.; van der Kaa, C. H.; Barentsz, J. O. Radiology 2009, 251, 408.
25. [25]
  (25) Bee, A.; Massart, R.; Neveu, S. J. Magn. Magn. Mater. 1995, 149, 6.
26. [26]
  (26) Rockenberger, J.; Scher, E. C.; Alivisatos, A. P. J. Am. Chem. Soc. 1999, 121, 11595.
27. [27]
  (27) Park, S.-J.; Kim, S.; Lee, S.; Khim, Z. G.; Char, K.; Hyeon, T. J. Am. Chem. Soc. 2000, 122, 8581.
28. [28]
  (28) Sun, S. H.; Zeng, H. J. Am. Chem. Soc. 2002, 124, 8204.
29. [29]
  (29) Sun, S. H.; Zeng, H.; Robinson, D. B.; Raoux, S.; Rice, P. M.; Wang, S. X.; Li, G. X. J. Am. Chem. Soc. 2004, 126, 273.
30. [30]
  (30) Jana, N. R.; Chen, Y.; Peng, X. G. Chem. Mater. 2004, 16, 3931.
31. [31]
  (31) Park, J.; An, K. J.; Hwang, Y. S.; Park, J. G.; Noh, H. J.; Kim, J. Y.; Park, J. H.; Hwang, N. M.; Hyeon, T. Nat. Mater. 2004, 3, 891.
32. [32]
  (32) Lee, J. H.; Huh, Y. M.; Jun, Y.; Seo, J.; Jang, J.; Song, H. T.; Kim, S.; Cho, E. J.; Yoon, H. G.; Suh, J. S.; Cheon, J. Nat. Med. 2007, 13, 95.
33. [33]
  (33) Jun, Y.-W.; Seo, J.-W.; Cheon, J. Acc. Chem. Res. 2008, 41, 179.
34. [34]
  (34) Jung, C. W.; Jacobs, P. Magn. Reson. Imaging 1995, 13, 661.
35. [35]
  (35) Wan, Y. X.; Hussain, S. M.; Krestin,G. P. Eur. J. Radiol. 2001, 11, 2319.
36. [36]
  (36) Josephson, L.; Tung, C. H.; Moore, A.; Weissleder, R. Bioconjugate Chem. 1999, 10, 186.
37. [37]
  (37) Jun, Y. W.; Huh, Y. M.; Choi, J. S.; Lee, J. H.; Song, H. T.; Kim, S.; Yoon, S.; Kim, K. S.; Shin, J. S.; Suh, J. S.; Cheon, J. J. Am. Chem. Soc. 2005, 127, 5732.
38. [38]
  (38) Xie, J.; Chen, K.; Lee, H. Y.; Xu, C. J.; Hsu, A. R.; Peng, S.; Chen, X. Y.; Sun, S. H. J. Am. Chem. Soc. 2008, 130, 7542.
39. [39]
  (39) Liu, S. J.; Jia, B.; Qiao, R. R.; Yang, Z.; Yu, Z. L.; Liu, Z. F.; Liu, K.; Shi, J. Y.; Han, O. Y.; Wang, F.; Gao, M. Y. Mol. Pharmceutics 2009, 6, 1074.
40. [40]
  (40) Xie,J.; Xu, C.; Kohler, N.; Hou, Y.; Sun, S. Adv. Mater. 2007, 19, 3163.
41. [41]
  (41) Bin Na, H.; Lee, I. S.; Seo, H.; Il Park, Y.; Lee, J. H.; Kim, S. W.; Hyeon, T. Chem. Commun. 2007, 5167.
42. [42]
  (42) Piao, Y.; Park, Y. I.; Lee, N.; Yoo, B.; Kim, B. H.; Choi, S. H.; Hyeon, T. J. Mater. Chem. 2011, 21, 11472.
43. [43]
  (43) Robinson, D. B.; Persson, H. H. J.; Zeng, H.; Li, G. X.; Pourmand, N.; Sun, S. H.; Wang, S. X. Langmuir 2005, 21, 3096.
44. [44]
  (44) Nitin, N.; LaConte, L. E. W.; Zurkiya, O.; Hu, X.; Bao, G. J. Biol. Inorg. Chem. 2004, 9, 706.
45. [45]
  (45) Pellegrino, T.; Manna, L.; Kudera, S.; Liedl, T.; Koktysh, D.; Rogach, A. L.; Keller, S.; Radler, J.; Natile, G.; Parak, W. J. Nano Lett. 2004, 4, 703.
46. [46]
  (46) Yu, W. W.; Chang, E.; Sayes, C. M.; Drezek, R.; Colvin, V. L. Nanotechnology 2006, 17, 4483.
47. [47]
  (47) Li, Z.; Chen, H.; Bao, H. B.; Gao, M. Y. Chem. Mater. 2004, 16, 1391.
48. [48]
  (48) Li, Z.; Sun, Q.; Gao, M. Y. Angew. Chem., Int. Edit 2005, 44, 123.
49. [49]
  (49) Lu, X. Y.; Niu, M.; Qiao, R. R.; Gao, M. Y. J. Phys. Chem. B 2008, 112, 14390.
50. [50]
  (50) Lu, X. Y.; Niu, M.; Yang, C. H.; Yi, L. X.; Qiao, R. R.; Du, M. H.; Gao, M. Y. Chin. Sci. Bull. 2010, 55, 3472.
51. [51]
  (51) Li, Z.; Wei, L.; Gao, M. Y.; Lei, H. Adv. Mater. 2005, 17, 1001.
52. [52]
  (52) Hu, F. Q.; Li, Z.; Tu, C. F.; Gao, M. Y. J. Colloid Interface Sci. 2007, 311, 469.
53. [53]
  (53) Liu, S. J.; Han, Y. C.; Qiao, R. R.; Zeng, J. F.; Jia, Q. J.; Wang, Y. L.; Gao, M. Y. J. Phys. Chem. C 2010, 114, 21270.
54. [54]
  (54) Jia, Q.; Zeng, J.; Qiao, R.; Jing, L.; Peng, L.; Gu, F.; Gao, M. J. Am. Chem. Soc. 2011, 133, 19512.
55. [55]
  (55) Liu, C. Y.; Jia, Q. J.; Yang, C. H.; Qiao, R. R.; Jing, L. H.; Wang, L. B.; Xu, C. L.; Gao, M. Y. Anal. Chem. 2011, 83, 6778.
56. [56]
  (56) Williams, D. F. Biomaterials 2008, 29, 2941.
57. [57]
  (57) Sun, C.; Lee, J. S. H.; Zhang, M. Q. Adv. Drug Deliv. Rev. 2008, 60, 1252.
58. [58]
  (58) Sun, C.; Sze, R.; Zhang, M. Q. J. Biomed. Mater. Res. Part A 2006, 78A, 550.
59. [59]
  (59) Yang, L. L.; Mao, H.; Wang, Y. A.; Cao, Z. H.; Peng, X. H.; Wang, X. X.; Duan, H. W.; Ni, C. C.; Yuan, Q. G.; Adams, G.; Smith, M. Q.; Wood, W. C.; Gao, X. H.; Nie, S. M. Small 2009, 5, 235.
60. [60]
  (60) Lu, J. J.; Wang, F.; Jin, Z. Y.; Zhong, D. R. Acta Acad. Med. Sin., 2008, 31, 124. [陆菁菁, 王芳, 金征宇, 钟定荣. 中国医学科学院学报, 2008, 31, 124.]
61. [61]
  (61) Sun, C.; Veiseh, O.; Gunn, J.; Fang, C.; Hansen, S.; Lee, D.; Sze, R.; Ellenbogen, R. G.; Olson, J.; Zhang, M. Small 2008, 4, 372.
62. [62]
  (62) Lee, H. Y.; Li, Z.; Chen, K.; Hsu, A. R.; Xu, C. J.; Xie, J.; Sun, S. H.; Chen, X. Y. J. Nucl. Med. 2008, 49, 1371.
63. [63]
  (63) Qiao, R. R.; Liu, K.; Jia, B.; Zeng, J. F.; Ouyang, H.; Wang, F.; Gao, M. Y. J Southeast Univ (Med Sci Edi) 2011, 30, 4. [乔瑞瑞, 刘侃, 贾兵, 曾剑峰, 欧阳汉, 王凡, 高明远. 东南大学学报(医学版) 2011, 30, 4.]
64. [64]
  (64) Montet, X.; Montet-Abou, K.; Reynolds, F.; Weissleder, R.; Josephson, L. Neoplasia 2006, 8, 214.
65. [65]
  (65) Shi, X. Y.; Wang, S. H.; Swanson, S. D.; Ge, S.; Cao, Z. Y.; Van Antwerp, M. E.; Landmark, K. J.; Baker, J. R. Adv. Mater. 2008, 20, 1671.
66. [66]
  (66) Cheon, J.; Lee, J. H. Acc. Chem. Res. 2008, 41, 1630.
67. [67]
  (67) Hsieh, C. H.; Kuo, J. W.; Lee, Y. J.; Chang, C. W.; Gelovani, J. G.; Liu, R. S. J. Nucl. Med. 2009, 50, 2049.
68. [68]
  (68) Lee, S.; Chen, X. Y. Mol. Imaging 2009, 8, 87.
69. [69]
  (69) Lin, K. M.; Hsu, C. H.; Chang, W. S. W.; Chen, C. T.; Lee, T. W.; Chen, C. T. Mol. Imaging. Biol. 2008, 10, 253.
70. [70]
  (70) Bartels, A. L.; Zeebregts, C. J.; Bijl, M.; Tio, R. A.; Slart, R. H. J. A. Ann. Nucl. Med. 2009, 23, 753.
71. [71]
  (71) Pop, M.; Sermesant, M.; Lepiller, D.; Truong, M. V.; McVeigh, E. R.; Crystal, E.; Dick, A.; Delingette, H.; Ayache, N.; Wright, G. A. Med. Image. Anal. 2009, 13, 370.
72. [72]
  (72) Choi, J.-S. ; Park, J. C.; Nah, H.; Woo, S.; Oh, J.; Kim, K. M.; Cheon, G. J.; Chang, Y.; Yoo, J.; Cheon, J. Angew. Chem., Int. Ed. 2008, 47, 6259.
73. [73]
  (73) Glaus, C.; Rossin, R.; Welch, M. J.; Bao, G. Bioconjugate Chem. 2010, 21, 715.
74. [74]
  (74) Yezhelyev, M. V.; Qi, L. F.; O'Regan, R. M.; Nie, S.; Gao, X. H. J. Am. Chem. Soc. 2008, 130, 9006.
75. [75]
  (75) Qi, L. F.; Gao, X. H. Acs Nano 2008, 2, 1403.
76. [76]
  (76) Veiseh, O.; Sun, C.; Fang, C.; Bhattarai, N.; Gunn, J.; Kievit, F.; Du, K.; Pullar, B.; Lee, D.; Ellenbogen, R. G.; Olson, J.; Zhang, M. Q. Cancer Res. 2009, 69, 6200.
77. [77]
  (77) Yang, L.; Mao, H.; Cao, Z. H.; Wang, Y. A.; Peng, X. H.; Wang, X. X.; Sajja, H. K.; Wang, L. Y.; Duan, H. W.; Ni, C. C.; Staley, C. A.; Wood, W. C.; Gao, X. H.; Nie, S. M. Gastroenterology 2009, 136, 1514.
78. [78]
  (78) Chen, K.; Xie, J.; Xu, H. Y.; Behera, D.; Michalski, M. H.; Biswal, S.; Wang, A.; Chen, X. Y. Biomaterials 2009, 30, 6912.
79. [79]
  (79) Xie, J.; Chen, K.; Huang, J.; Lee, S.; Wang, J. H.; Gao, J.; Li, X. G.; Chen, X. Y. Biomaterials 2010, 31, 3016.
1. [1]
  Tingting XU , Wenjing ZHANG , Yongbo SONG . Research advances of atomic precision coinage metal nanoclusters in tumor therapy. Chinese Journal of Inorganic Chemistry, 2024, 40(12): 2275-2285. doi: 10.11862/CJIC.20240229
2. [2]
  Aiai WANG , Lu ZHAO , Yunfeng BAI , Feng FENG . Research progress of bimetallic organic framework in tumor diagnosis and treatment. Chinese Journal of Inorganic Chemistry, 2024, 40(10): 1825-1839. doi: 10.11862/CJIC.20240225
3. [3]
  Zhaoxin LI , Ruibo WEI , Min ZHANG , Zefeng WANG , Jing ZHENG , Jianbo LIU . Advancements in the construction of inorganic protocells and their cell mimic and bio-catalytical applications. Chinese Journal of Inorganic Chemistry, 2024, 40(12): 2286-2302. doi: 10.11862/CJIC.20240235
4. [4]
  Hao Wu , Zhen Liu , Dachang Bai . ¹H NMR Spectrum of Amide Compounds. University Chemistry, 2024, 39(3): 231-238. doi: 10.3866/PKU.DXHX202309020
5. [5]
  Jiahui CHEN , Tingting ZHENG , Xiuyun ZHANG , Wei LÜ . Research progress of near-infrared absorption inorganic nanomaterials in photothermal and photodynamic therapy of tumors. Chinese Journal of Inorganic Chemistry, 2024, 40(12): 2396-2414. doi: 10.11862/CJIC.20240106
6. [6]
  Jinkang Jin , Yidian Sheng , Ping Lu , Zhan Lu . Introducing a Website for Learning Nuclear Magnetic Resonance (NMR) Spectrum Analysis. University Chemistry, 2024, 39(11): 388-396. doi: 10.12461/PKU.DXHX202403054
7. [7]
  Haolin Zhan , Qiyuan Fang , Jiawei Liu , Xiaoqi Shi , Xinyu Chen , Yuqing Huang , Zhong Chen . Noise Reduction of Nuclear Magnetic Resonance Spectroscopy Using Lightweight Deep Neural Networ. Acta Physico-Chimica Sinica, 2025, 41(2): 100017-. doi: 10.3866/PKU.WHXB202310045
8. [8]
  Haiyang Jin , Yonghai Hui , Yongfei Zhang , Lijun Gao , Yun Wang . Application and Exploration of Nuclear Magnetic Resonance Spectrometer in Undergraduate Basic Laboratory Teaching. University Chemistry, 2025, 40(3): 245-250. doi: 10.12461/PKU.DXHX202406022
9. [9]
  Zehua Zhang , Haitao Yu , Yanyu Qi . 多重共振TADF分子的设计策略. Acta Physico-Chimica Sinica, 2025, 41(1): 2309042-. doi: 10.3866/PKU.WHXB202309042
10. [10]
  Zhuoming Liang , Ming Chen , Zhiwen Zheng , Kai Chen . Multidimensional Studies on Ketone-Enol Tautomerism of 1,3-Diketones By ¹H NMR. University Chemistry, 2024, 39(7): 361-367. doi: 10.3866/PKU.DXHX202311029
11. [11]
  Yongjie ZHANG , Bintong HUANG , Yueming ZHAI . Research progress of formation mechanism and characterization techniques of protein corona on the surface of nanoparticles. Chinese Journal of Inorganic Chemistry, 2024, 40(12): 2318-2334. doi: 10.11862/CJIC.20240247
12. [12]
  Zhuo WANG , Xiaotong LI , Zhipeng HU , Junqiao PAN . Three-dimensional porous carbon decorated with nano bismuth particles: Preparation and sodium storage properties. Chinese Journal of Inorganic Chemistry, 2025, 41(2): 267-274. doi: 10.11862/CJIC.20240223
13. [13]
  Ping Song , Nan Zhang , Jie Wang , Rui Yan , Zhiqiang Wang , Yingxue Jin . Experimental Teaching Design on Synthesis and Antitumor Activity Study of Cu-Pyropheophorbide-a Methyl Ester. University Chemistry, 2024, 39(6): 278-286. doi: 10.3866/PKU.DXHX202310087
14. [14]
  Jing WU , Puzhen HUI , Huilin ZHENG , Pingchuan YUAN , Chunfei WANG , Hui WANG , Xiaoxia GU . Synthesis, crystal structures, and antitumor activities of transition metal complexes incorporating a naphthol-aldehyde Schiff base ligand. Chinese Journal of Inorganic Chemistry, 2024, 40(12): 2422-2428. doi: 10.11862/CJIC.20240278
15. [15]
  Wenjun Yang , Qiaoling Tan , Wenjiao Xie , Xiaoyu Pan , Youyong Yuan . Construction and Characterization of Calcium Alginate Microparticle Drug Delivery System: A Novel Design and Teaching Practice in Polymer Experiments. University Chemistry, 2025, 40(3): 371-380. doi: 10.12461/PKU.DXHX202405150
16. [16]
  Junjie Zhang , Yue Wang , Qiuhan Wu , Ruquan Shen , Han Liu , Xinhua Duan . Preparation and Selective Separation of Lightweight Magnetic Molecularly Imprinted Polymers for Trace Tetracycline Detection in Milk. University Chemistry, 2024, 39(5): 251-257. doi: 10.3866/PKU.DXHX202311084
17. [17]
  Yuhao SUN , Qingzhe DONG , Lei ZHAO , Xiaodan JIANG , Hailing GUO , Xianglong MENG , Yongmei GUO . Synthesis and antibacterial properties of silver-loaded sod-based zeolite. Chinese Journal of Inorganic Chemistry, 2024, 40(4): 761-770. doi: 10.11862/CJIC.20230169
18. [18]
  Siyu HOU , Weiyao LI , Jiadong LIU , Fei WANG , Wensi LIU , Jing YANG , Ying ZHANG . Preparation and catalytic performance of magnetic nano iron oxide by oxidation co-precipitation method. Chinese Journal of Inorganic Chemistry, 2024, 40(8): 1577-1582. doi: 10.11862/CJIC.20230469
19. [19]
  Chenye An , Abiduweili Sikandaier , Xue Guo , Yukun Zhu , Hua Tang , Dongjiang Yang . 红磷纳米颗粒嵌入花状CeO₂分级S型异质结高效光催化产氢. Acta Physico-Chimica Sinica, 2024, 40(11): 2405019-. doi: 10.3866/PKU.WHXB202405019
20. [20]
  Yuanpei ZHANG , Jiahong WANG , Jinming HUANG , Zhi HU . Preparation of magnetic mesoporous carbon loaded nano zero-valent iron for removal of Cr(Ⅲ) organic complexes from high-salt wastewater. Chinese Journal of Inorganic Chemistry, 2024, 40(9): 1731-1742. doi: 10.11862/CJIC.20240077

Get Citation

PDF

XML

Metrics

PDF Downloads(2172)
Abstract views(3277)
HTML views(10)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142