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Citation: Jiarong Feng, Yejie Duan, Chu Chu, Dezhen Xie, Qiu'e Cao, Peng Liu. Preparation and Application of a Streptomycin Molecularly Imprinted Electrochemical Sensor: A Suggested Comprehensive Analytical Chemical Experiment[J]. University Chemistry, ;2024, 39(8): 295-305. doi: 10.3866/PKU.DXHX202401016 shu

Preparation and Application of a Streptomycin Molecularly Imprinted Electrochemical Sensor: A Suggested Comprehensive Analytical Chemical Experiment

School of Chemical and Technology, Yunnan University, National Demonstration Center for Experimental Chemistry and Chemical Engineering Education (Yunnan University), Kunming 650091, China

Received Date: 5 January 2024
Revised Date: 11 March 2024

This paper outlines a comprehensive, inquiry-based instrumental analysis experiment to integrate molecular imprinting technology into undergraduate education. The experiment commences with the fabrication of a streptomycin molecular imprinting electrochemical sensor (STR-MIM/GCE) via the electropolymerization method. Subsequent characterization of the sensor employs cyclic voltammetry and scanning electron microscopy. Utilizing potassium ferricyanide as a probe, a differential pulse voltammetry technique is developed for the electrochemical quantification of streptomycin, with milk serving as a real-world sample for testing. This experiment involves the modification and characterization of electrode surface, alongside the development and application of electrochemical analysis methods. The experiment uses readily available and cost-effective reagents, avoids the need for sophisticated instrumentation, and is designed with a duration suitable for undergraduate coursework.
- Molecular imprinting technology,
- Electrochemical sensor,
- Streptomycin
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