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Citation: Tao Wen, Tao Zhang, Changguo Sun, Jinyu Liu. Preparation of Dess-Martin Reagent and Its Application in Oxidizing Cyclohexanol[J]. University Chemistry, ;2024, 39(5): 20-26. doi: 10.3866/PKU.DXHX202309055 shu

Preparation of Dess-Martin Reagent and Its Application in Oxidizing Cyclohexanol

College of Materials and Chemistry & Chemical Engineering, Chengdu University of Technology, Chengdu 610059, China

Received Date: 18 September 2023
Revised Date: 5 January 2024

Preparation of cyclohexanone is a classic “hands-on” organic chemistry experiment widely used in undergraduate teaching. However, conventional experiments often involve the use of non-environmentally friendly high-cost heavy metal oxidants, limiting the teaching process to the development of students’ experimental skills. In response to this, we have transformed the experiment into a design-oriented approach. Students are tasked with consulting literature, researching, and exploring greener and more environmentally friendly oxidation systems. By evaluating the merits of various oxidation systems, determining the types of oxidants, and designing experimental procedures, students complete the experiment. This innovative approach enhances the experiment’s complexity, promotes innovation, and introduces challenges. It not only solidifies students’ practical laboratory skills but also cultivates their ability to discover, analyze, and solve problems, fostering innovative thinking and awareness of green chemistry.
- Design experiment,
- Green oxidation,
- Dess-Martin reagent,
- Preparation of cyclohexanone
1. [1]
2. [2]
3. [3]
4. [4]
  McKillop, A.; Young, D. W. Synthesis 1979, 401.
5. [5]
  Sharma, A. K.; Ku, T.; Dawson, A. D.; Swern, D. J. Org. Chem. 1975, 40, 2758.
6. [6]
  Wirth, T. Angew. Chem. Int. Ed. 2001, 40, 2812.
7. [7]
  Dess, D. B.; Martin, J. C. J. Org. Chem. 1983, 48, 4155.
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